Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics

Intraocular Pressure Clinical Trial

Official title:

Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics; a Randomized, Double-blind Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03589638
• Other study ID #: Asozkan 6
• Status: Completed
• Phase: N/A
• Start date: June 20, 2018
• Est. completion date: August 8, 2018

Study information

• Verified date: July 2021
• Source: Inonu University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this study, participants aimed to compare the effects of direct laryngoscopic endotracheal intubation and videolaryngoscopic intubation with C-MAC videolaryngoscope and McGrath videolaryngoscope on intraocular pressure and hemodynamics.

Description:

The maintenance of airway opened is one of the main responsibility of the anesthetist. Intubation procedure during anesthesia application benefits such as airway opening, airway and breathing control, aspiration hazard, respiratory effort and dead space reduction, surgical comfort and airway control during resuscitation. Laryngoscopy and tracheal intubation increases in heart rate, blood pressure and the intraocular pressure. The sympathetic-adrenal activity caused by the stimulation of the laryngeal and tracheal tissues is responsible for these negative effects. Endotracheal intubation with videolaryngoscopy is an alternative method used in airway management. Laryngoscopy and tracheal intubation under general anesthesia and laryngeal mask and airway control techniques cause different hemodynamic and catecholamine levels.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 3
• Est. completion date: August 8, 2018
• Est. primary completion date: August 8, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• American Society of Anesthesiologist Score 1-2

• Mallampati 1 ve 2

Exclusion Criteria:

• Glaucoma,

• Diabetes mellitus

• Cardiovascular and pulmonary disease

• American Society of Anesthesiologist Score III-IV

• Bdoy mass index greater than 35

• Difficult intubation history

• Obstetric surgery

• Propofol, fentanyl, rocuronium contraindication

Related Conditions & MeSH terms

• Anesthesiology Devices Associated With Adverse Incidents
• Intraocular Pressure

Intervention

Device:
• Direct laryngoscope
Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.
• C-MAC videolaryngoscope
Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.
• McGrath videolaryngoscope
Endotracheal intubation was applied by anesthesiologist wtih direct laryngoscope. SAP (systolic arterial pressure), DAP (diastolic arterial artery pressure), MAP (mean arterial pressure) were measured before and 5 minutes after intubation, , Heart rate (HR), SPO2 (oxygen saturation by pulse oximetry), PI (perfusion index), and intraocular pressure values measured by the eye clinician using the device.

Locations

Country	Name	City	State
Turkey	Inonu University Medical Faculty	Malatya

Sponsors (1)

Lead Sponsor	Collaborator
Inonu University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	intraocular pressure	The relevant values will be measured in the determined time.	From beginning of Anesthesia to 10th minute of surgery
Secondary	mean arterial pressure	The relevant values will be measured in the determined time.	From beginning of Anesthesia to 10th minute of surgery
Secondary	systolic arterial pressure	The relevant values will be measured in the determined time.	From beginning of Anesthesia to 10th minute of surgery
Secondary	diastolic arterial pressure	The relevant values will be measured in the determined time.	From beginning of Anesthesia to 10th minute of surgery
Secondary	heart rate	The relevant values will be measured in the determined time.	From beginning of Anesthesia to 10th minute of surgery
Secondary	peripheral oxygen saturation	The relevant values will be measured in the determined time.	From beginning of Anesthesia to 10th minute of surgery