IOP Elevation Study

Status Recruiting

Clinical Trial Summary

The purpose of this study is to improve understanding of the pathophysiologic process that leads to the development of glaucamotous damage. The mechanism by which vision loss in glaucoma occurs is still unknown, but it is clear that increased intraocular pressure (IOP) is a major risk factor. It is also thought that the LC is a site of primary damage during pathogenesis of the disease. This prospective study with determine the in-vivo mechanical response to IOP modulation at the level of the ONH and LC.

Clinical Trial Description

The present study will briefly increase the pressure in eyes of living subjects and examine the effect of elevated intraocular pressure on optic nerve topography and position during pressure elevation using optical coherence tomography imaging of the posterior eye. Outcome measures will include measurements in microns based on these images quantifying the deformation of the lamina cribrosa. ;

Study Design

Related Conditions & MeSH terms

Intraocular Pressure

Clinical Trial Details

NCT number	NCT03400137
Study type	Interventional
Source	NYU Langone Health
Contact	Jamika Singleton-Garvin
Phone	+1 929 455 5539
Email	Jamika.Singleton-Garvin@nyulangone.org
Status	Recruiting
Phase	N/A
Start date	March 7, 2018
Completion date	May 8, 2024

View Details

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