Fluoroscopic &Ultrasonographic Guidance of Superior Hypogastric Plexus Neurolysis in Intractable Pelvic Pain

Intractable Pelvic Cancer Pain Clinical Trial

Official title:

The Role of Double Modality " Fluoroscopic &Ultrasonographic " Guidance of Superior Hypogastric Plexus Neurolysis in Treating Intractable Pelvic Cancer Pain: a Comparative Study.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03606811
• Other study ID #: IORG0003301
• Status: Completed
• Phase: N/A
• Start date: August 5, 2018
• Est. completion date: August 15, 2019

Study information

• Verified date: January 2020
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

fluoroscopic group & includes 30 patients where SHPB will be done Fluoroscopic-guided (the posterior oblique trajectory technique.the double modality group & includes 30 patients where SHPB will be done using our described new technique of performing the modified Mishra technique by injecting 3-5 ml of contrast media (lohexol=omnipaque) after getting the target position.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: August 15, 2019
• Est. primary completion date: August 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Age > 18 years.

• Intractable pelvic cancer pain (VAS > 40 mm)

• Pain is refractory to pharmacotherapy (both opioids and adjuvant therapy) or opioids' side effects are not tolerated.

Exclusion criteria

• Local or systemic sepsis.

• Uncorrectable coagulopathy.

• Neuropsychiatric illness.

• History of drug abuse.

• Pregnant or lactating patients.

• Distorted local anatomy.

• Patients who are known to be allergic to the used medications.

• Cardiovascular or respiratory instability.

Related Conditions & MeSH terms

• Cancer Pain
• Intractable Pelvic Cancer Pain
• Pelvic Neoplasms

Intervention

Procedure:
• fluroscopic guided block
SHPB will be done Fluoroscopic-guided (the posterior oblique trajectory technique.
• double modality (ultrasound and fluroscopic) guided block
SHPB will be done using our described new technique of performing the modified Mishra technique by injecting 3-5 ml of contrast media (lohexol=omnipaque) after getting the target position. Then C-arm pictures will be checked (both P-A & dead lateral)

Locations

Country	Name	City	State
Egypt	NCI, Cairo university	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pain relief will be assessed by VAS	pain relief will be assessed by VAS (visual Analogue score) which is 100 mscale with left (0) end means no pain & right (10) end means the worst possible pain	12 weeks