Intracranial Pressure Clinical Trial
Official title:
Correlation Between Intracranial Pressure as Measured by Lumbar Puncture Manometry and Percentage Body Fat as Measured by Air-displacement Plethysmography
Verified date | May 2017 |
Source | Gloucestershire Hospitals NHS Foundation Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Background: It has already been established that there is a weak positive relationship
between increased intracranial pressure (ICP), as measured by lumbar puncture manometry, and
increased Body Mass Index (BMI). This is also observed clinically in some patients with
idiopathic intracranial hypertension, who typically have raised BMI. The relationship
between BMI and percentage body fat is non-linear, especially at BMI > 40. The Bod Pod
device enables non-invasive body composition profiling, including accurate calculation of
percentage body fat, without the use of radiation.
Aim: To examine the relationship between intracranial pressure as measured by lumbar
puncture manometry and percentage body fat as measured by air-displacement plethysmography
(Bod Pod)
Methods: 100 patients undergoing routine diagnostic and therapeutic lumbar punctures for a
variety of non-emergency neurological conditions will be recruited. Cerebrospinal fluid
opening pressure will be measured using standard manometry techniques. Blood pressure,
height, weight, collar size, waist size and hip size will be measured. Body composition
profiling will be carried out using the Bod Pod.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | March 2018 |
Est. primary completion date | March 2018 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Able to give informed consent Exclusion Criteria: |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Benjamin Wakerley | Gloucester | Gloucestershire |
Lead Sponsor | Collaborator |
---|---|
Gloucestershire Hospitals NHS Foundation Trust |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Intracranial pressure vs % body fat using BodPOD | Correlation between intracranial pressure as measured by lumbar puncture manometry and percentage body fat as measured by air-displacement plethysmography. | 3 years | |
Secondary | intracranial pressure vs body mass index | Correlation between intracranial pressure as measured by lumbar puncture manometry and body mass index. | 3 years |
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