Brain Injury Clinical Trial
Official title:
A Phase IV Single Center Cross Over Clinical Study Comparing Two Different Sedations Strategies for Mechanically Ventilated Patients With Neurological Critical Illness
The purpose of this study is to evaluate brain injury when two different drugs (propofol and precedex) are used to sedate patients who need a neurologic exam.
The hypothesis is that a neurologic exam performed when the subject has continuous infusion of precedex will result in less brain injury (where the lactate/pyruvate ratio indicates injury) then when a neurologic exam is performed on subjects receiving propofol, because that exam requires that the propofol infusion be stopped. ;
Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02710123 -
Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion
|
N/A | |
Recruiting |
NCT02777060 -
Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures
|
N/A | |
Completed |
NCT02262286 -
MIND (Management of Traumatic Brain Injury Diagnosis)
|
N/A | |
Completed |
NCT01461902 -
Vasospasm in Pediatric Traumatic Brain Injury
|
N/A | |
Recruiting |
NCT01198964 -
Optimization of Human Cortical Stimulation
|
||
Active, not recruiting |
NCT01207050 -
Effect of Rozerem on Sleep Among People With Traumatic Brain Injury
|
Phase 4 | |
Completed |
NCT00875329 -
Traumatic Brain Injury (TBI) Screening Instruments
|
N/A | |
Completed |
NCT01201863 -
Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy
|
Phase 4 | |
Completed |
NCT01035606 -
Training in Goal-directed Attention Regulation for Individuals With Brain Injury
|
N/A | |
Completed |
NCT01059890 -
Cerebral Antibiotics Distribution After Acute Brain Injury
|
Phase 1 | |
Completed |
NCT00571623 -
Automated Chest Physiotherapy to Improve Outcomes in Neuro
|
N/A | |
Completed |
NCT00596765 -
Neuropsychological Cognitive Behavioral Therapy for Patients With Acquired Brain Injury
|
N/A | |
Completed |
NCT00336466 -
The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS)
|
Phase 2 | |
Recruiting |
NCT05105763 -
Biofeedback Gait Retraining for Stiff Knee Gait Correction
|
N/A | |
Recruiting |
NCT02495558 -
Cough Assessment in Patients With Severe Acquired Brain Injury
|
N/A | |
Completed |
NCT02100592 -
Early Verticalization in neuroICU With ERIGO: a Safety and Feasibility Study
|
Phase 1/Phase 2 | |
Completed |
NCT00797680 -
Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest
|
Phase 2 | |
Completed |
NCT00018499 -
Genotype Influence on Recovery After Traumatic Brain Injury
|
N/A | |
Recruiting |
NCT02567201 -
Electrophysiological Evaluation of Voluntary Attention
|
N/A | |
Withdrawn |
NCT05581927 -
Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE)
|
N/A |