Clinical Trials Logo
  1. Home
  2. Intracranial Pressure Increase
  3. NCT04046523

Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy — ICP Waveform  

Intracranial Pressure Increase Clinical Trial

Official title:
Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy

Clinical Trial Summary

This study will test the use of video ophthalmoscope to provide information about intracranial pressure without the use of invasive methods, anesthesia or contact with the eye.

Clinical Trial Description

The monitoring of intracranial pressure (ICP) is crucial in head injuries and pathologies such as brain edema, arachnoid cyst, craniosynostosis or, in very-low-birthweight infants, post-hemorrhagic hydrocephalus. Some current methods of ICP are invasive and, in the case of lumbar puncture, require anesthesia, which can distort the measurement by 5-10 mmHg. The golden clinical standard is direct measurement using a surgically-implanted intraventricular drain connected to an external pressure transducer ("ICP probe"). However, this method carries risks such as hemorrhage, malfunction, obstruction or infection . The risk in pediatric patients is up to 5% and in adults the risk of fatal hemorrhage is 4-5% in patients with subdural and intraparenchymal monitoring devices. Due to these risks and the financial burden on patients, there have been attempts to develop tools for non-invasive ICP estimation. This study will test the use of a video ophthalmoscope that will calculate the relative waveform of intracranial pressure and provide information about intracranial compliance without the use of anesthesia, invasive methods or contact with the eye. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04046523
Study type Interventional
Source University of Minnesota
Contact Igor Nestrasil, MD, PhD
Phone 612-625-0496
Email nestr007@umn.edu
Status Recruiting
Phase N/A
Start date August 31, 2019
Completion date July 31, 2030
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT03227354 - Validation of Non-invasive Absolute Intracranial Pressure Monitoring N/A
Completed NCT03641443 - non_invasive_aICP_Tumor N/A
Not yet recruiting NCT03828032 - Multi-parameters'Change Process During Dehydration Therapy on Brain Edema Patients. N/A
Terminated NCT03286426 - Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure N/A
Completed NCT03782077 - Change of Optic Nerve Sheath Diameter After Deflation of Pneumatic Tourniquet
Completed NCT03195881 - Neuroprognostication Using Optic Nerve Sheath Diameter
Completed NCT04446013 - Comparison of ONSD and rSO2 Measurements Between General and Spinal Anesthesia in C-Section N/A
Completed NCT03418753 - Non-invasive Diagnostic for Assessing Elevated Intracranial Pressure
Active, not recruiting NCT05609071 - Technology of Intracranial Pressure Estimation by Single-Channel EEG in Brain Disease
Completed NCT05286697 - The Effect of Optic Nerve Diameter on Postoperative Cognitive Function in Laparoscopic Hysterectomy N/A
Completed NCT06048900 - Evaluation of the Effect of Trendelenburg Position Duration on Intracranial Pressure N/A
Active, not recruiting NCT05731765 - SVP Detection Using Machine Learning
Recruiting NCT05346471 - Infra- and Supratentorial Neuromonitoring N/A
Recruiting NCT03344432 - Correlation Intraocular Pressure With Intracranial Pressure N/A
Recruiting NCT05931991 - Intra-operative Evaluation of the External Ventricular Drain Catheter Position With Structured Light for Patients (Bullseye EVD)
Completed NCT04004923 - Intracranial Pressure in Monopolar and Bipolar Hysteroscopy N/A
Recruiting NCT04675216 - Posterior Fossa Intracranial Pressure (ICP) Measurement: Clinical Study
Not yet recruiting NCT05445271 - Optic Nerve Sheath Diameter in Pediatric Patients N/A
Completed NCT05499754 - Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter
Completed NCT04224532 - The Effect of Pneumoperitoneum Timing on Intracranial Pressure in Laparoscopy N/A