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Intracranial Pressure Increase clinical trials

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NCT ID: NCT06464419 Recruiting - Clinical trials for Intracranial Pressure Increase

Effect of Lithotomy Position on Optic Nerve Sheath Diameter

Start date: June 10, 2024
Phase:
Study type: Observational

In this study, the effect of increased venous return and increased intra-abdominal pressure on intracranial pressure in the lithotomy position was evaluated.

NCT ID: NCT06451289 Completed - Seizures Clinical Trials

Study on Optic Nerve Sheath Diameter Measurements in Prolonged Pediatric Seizures

ONSD
Start date: September 1, 2020
Phase:
Study type: Observational

A total of 88 postictal children with generalized or focal seizures were included in the study. The ONSD and ONSD/ETD ratio was measured independently by a pediatric neurologist and pediatric emergency expert, three times in both eyes using non-contrasted computed tomography taken within one hour after the seizure. The characteristics of seizures (duration, etiology, initiated treatment, and frequency) were recorded. Non-traumatic patients with normal head computed tomography findings at the hospital admission were considered as the control group (n=109).

NCT ID: NCT06428461 Not yet recruiting - Clinical trials for Intracranial Pressure Increase

Evaluation of Supraclavicular Brachial Plexus Blocks at Various Volumes: Impact on Optic Nerve Sheath Diameter

Start date: May 20, 2024
Phase: N/A
Study type: Interventional

This study aimed to evaluate the anesthesia adequacy, side effects, and complication rates, as well as the postoperative pain relief effectiveness of supraclavicular brachial plexus blocks administered at different volumes under ultrasound guidance. Additionally, the investigators utilized ultrasound to measure optic nerve sheath diameters and investigated their relationship with intracranial pressure across varying block volumes.

NCT ID: NCT06403592 Recruiting - Clinical trials for Intracranial Pressure Increase

The Effect of a Laryngeal Mask Airway on Optic Nerve Sheath Diameter

ONSD laryngeal
Start date: March 25, 2024
Phase:
Study type: Observational

The goal of this observational trial is to study the effect of a laryngeal airway mask on the optic nerve sheath diameter, as a surrogate for intracranial pressure. The optic nerve sheath diameter of participants will be measured under general anesthesia, before, during and after insertion of a laryngeal airway mask.

NCT ID: NCT06288659 Recruiting - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial

ASTIM-MT
Start date: May 20, 2024
Phase: N/A
Study type: Interventional

ASTIM is a multicenter, prospective, randomised, blinded end-point assessed trial, to investigate the efficacy and safety of treatment based on intracranial pressure monitoring in improving the prognosis of patients with aneurysmal subarachnoid hemorrhage.

NCT ID: NCT06209034 Recruiting - Clinical trials for Intracranial Pressure Increase

Intraoperative Optic Nerve Sheath Diameter Changes After Laparoscopic Surgery

Start date: December 30, 2023
Phase: N/A
Study type: Interventional

Laparoscopic surgery is a widely used alternative to open surgery; Advantages include reduced bleeding and pain intensity, shorter hospital stay, and improved cosmetic results. Laparoscopic surgery involves the creation of a carbon dioxide (CO2) pneumoperitoneum to facilitate a clear surgical view, which can result in increased intracranial pressure (ICP). Ultrasonographic measurement of optic nerve sheath diameter (ONSD) is a simple, non-invasive, yet reliable technique for ICP assessment.Ultrasonographic assessment of optic nerve sheath diameter (ONSD) has been proposed as a non-invasive measurement of intracranial pressure.

NCT ID: NCT06048900 Completed - Clinical trials for Intracranial Pressure Increase

Evaluation of the Effect of Trendelenburg Position Duration on Intracranial Pressure

Start date: March 10, 2021
Phase: N/A
Study type: Interventional

The Lloyd Davies position is a position used in laparoscopic hysterectomies where the head is lowered 45 degrees and the legs are bent from the knee area.It is a version of the Trendelenburg position. Both this position and for laparoscopic surgery carbon dioxide (CO2) gas given into the abdomen, causes problems for the patient. Increased abdominal and thoracic pressure impairs venous return and increases intracranial pressure. Optic nerve sheath diameter can be measured by placing an ultrasound probe over the eye. It is possible to follow up the increase in intracranial pressure with this diameter measurement. In this study, it was planned to measure the optic nerve sheath diameter by ultrasound in patients who will undergo laparoscopic hysterectomy. It is aimed to observe the changes in the increase in intracranial pressure as the time lengthens with the measurements to be made at certain intervals during the operation. Secondary aim is to determine whether there is a cut-off value where the intracranial pressure starts to increase.

NCT ID: NCT05931991 Recruiting - Clinical trials for Intracranial Pressure Increase

Intra-operative Evaluation of the External Ventricular Drain Catheter Position With Structured Light for Patients (Bullseye EVD)

Start date: July 7, 2023
Phase:
Study type: Observational [Patient Registry]

The placement of external ventricular drainage (EVD) is a life-saving procedure used to relieve high pressures in the brain. Often performed at the bedside, a small tube (catheter) is inserted into one ventricle of the brain to drain cerebrospinal fluid and release the pressure build up. In standard practice, EVDs are placed freehand and initial catheter malpositioning occurs in up to ~60% of procedures. Currently, there are no adequate means to verify the position of the catheter before insertion which is a significant impediment to ensure accurate positioning. This non-interventional study aims to validate a novel technology, Bullseye EVD, for verifying the position of the EVD catheter during these emergency procedures.

NCT ID: NCT05731765 Active, not recruiting - Clinical trials for Intracranial Pressure Increase

SVP Detection Using Machine Learning

SVP-ML
Start date: March 1, 2023
Phase:
Study type: Observational

This diagnostic study will use 410 retrospectively captured fundal videos to develop ML systems that detect SVPs and quantify ICP. The ground truth will be generated from the annotations of two independent, masked clinicians, with arbitration by an ophthalmology consultant in cases of disagreement.

NCT ID: NCT05668208 Completed - Clinical trials for Intracranial Pressure Increase

Do Extraperitoneal Laparoscopic Surgeries Increase Intracranial Pressure?

Start date: January 6, 2023
Phase: N/A
Study type: Interventional

When the literature is examined, it has been reported in many studies that intracranial pressure increases due to laparoscopic procedures performed in the intraperitoneal area. The mechanism of increased intracranial pressure (ICP) associated with insufflation is most likely due to impaired venous drainage of the lumbar venous plexus at increased intra-abdominal pressure. Changes in ICP can be monitored by ultrasonographic measurement of optic nerve sheath diameter (ONSD), which is a generally accepted simple, reliable and non-invasive ICP measurement technique. In meta-analyses conducted on this subject, it has been revealed that ICP elevation during laparoscopy can be observed with a significant increase in ONSD in the early (0 30 minutes) and late (30-120 minutes) periods during carbondioxid (CO2) pneumoperitoneum. However, the effect of laparoscopic procedures performed in the extraperitoneal area on the central nervous system is not clear. There is not found any study in the literature comparing laparoscopic procedures, especially performed extraperitoneally and transperitoneally, and their effects on intracranial pressure. The aim of the study compare to laparoscopic cholecystectomy performed in the transperitoneal area and (totally extra-peritoneal) TEP inguinal hernia repair performed in the extraperitoneal area in terms of intracranial pressure relationship.