Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome — sICASBLM

Intracranial Artery Stenosis Clinical Trial

Official title:
A Prospective Observational Study on the Effect of Improving Blood Lipid Management on the Clinical Prognosis of Symptomatic Intracranial Atherosclerotic Stenosis（sICASBLM）

Status Recruiting

Clinical Trial Summary

sICASBLM is a prospective controlled trial, to asses the impact of improving blood lipid management on clinical outcome of moderate to severe symptomatic intracranial atherosclerotic stenosis patients (LDL-C>1.8mmol/L) without endovascular therapy.

Clinical Trial Description

sICASBLM aims to determine the effectiveness of conventional lipid management combined with PCSK9 inhibitors compared to conventional lipid management (atorvastatin 20-40mg or rosuvastatin 10-20mg or simvastatin 20-40mg) in reducing the incidence of recurrent stroke in patients with moderate to severe symptomatic intracranial atherosclerotic stenosis (LDL-C>1.8mmol/L) without endovascular therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05397405
Study type	Interventional
Source	Nanjing First Hospital, Nanjing Medical University
Contact	Junshan Zhou
Phone	8602587726218
Email	zhjsh333@126.com
Status	Recruiting
Phase	N/A
Start date	May 23, 2022
Completion date	May 1, 2024

View Details

See also
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Recruiting	`NCT05692882` - A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China	N/A
Recruiting	`NCT01665235` - Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis	N/A