Intracranial Aneurysms Clinical Trial
Official title:
Detection of Intracranial Aneurysm With Non-enhanced, Three-dimensional Time-of-flight Magnetic Resonance Angiography(3D−TOF−MRA): a Prospective Comparison With Three-dimensional Reconstructed Digital Subtraction Angiography (3D RDSA)
The Chinese Cerebral Aneurysms Survey is a continuing prospective study to evaluate the effectiveness of unenhanced, three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) with volume rendering (VR) at 3-T in the detection of intracranial aneurysms.
Recent years,three-dimensional time-of-flight MRA (3D-TOF-MRA) has become a useful,
contrast-free method for observing intracranial vessels and is widely utilized as a
screening examination for intracranial aneurysms. The studies available in Medline show
mixed results.Some of these studies just included MRI/MRA in the analysis, which have a high
rate of false-positives and are unreliable, and some were lack of control (ruptured
aneurysm), precise numbers of false-positive results, standard images process and review, or
corroborative IADSA in some patients. Furthermore, most previous studies included small
sample size with aneurysm detection at 0.5-T or 1.5-T MR. Thus, these results have been
inconclusive because of certain pitfalls in these studies.
Since 2007, we have conducted a clinical study to objective detection of intracranial
aneurysms in our routine diagnostic work-up of intracranial aneurysms by our
neuroradiologists using a standard procedure with 3D-TOF-MRA with VR at 3T. The
investigators want to establish the quality data to prospectively compare 3D-TOF-MRA with VR
at 3T vs 3D-RDSA in the diagnosis of intracranial aneurysms in a largest cohort of patients
and test it accuracy in screening for suspected patients
;
Observational Model: Cohort, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02879175 -
Patients' Follow-up After Subarachnoid Haemorrhage Caused by Ruptured Intracranial Aneurysms
|
||
Completed |
NCT01139892 -
The Canadian UnRuptured Endovascular Versus Surgery Trial (CURES)
|
||
Recruiting |
NCT06411418 -
Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm
|
N/A | |
Completed |
NCT02312856 -
Adjunctive Neurovascular Support for Wide-neck Aneurysm Embolization and Reconstruction
|
N/A | |
Recruiting |
NCT01054391 -
Neurovascular Embolization Cover for Treatment of Intracranial Aneurysms and Carotid/Vertebrobasilar Fistulae
|
N/A | |
Completed |
NCT02657772 -
Ultra Coils From Start to Finish for the Endovascular Repair of Small Intracranial Aneurysms
|
||
Completed |
NCT01465841 -
Study of the Penumbra Coil 400 System to Treat Aneurysm
|
N/A | |
Enrolling by invitation |
NCT05453240 -
Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the LVIS Device
|
||
Completed |
NCT03550638 -
Coil System(Ton-bridgeMT) for Endovascular Embolization of Cranial Aneurysms
|
N/A | |
Terminated |
NCT02122133 -
CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400
|
||
Completed |
NCT01541254 -
Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device
|
Phase 2/Phase 3 | |
Terminated |
NCT01320306 -
Intracranial Aneurysms and Cognitive Function
|
||
Recruiting |
NCT01084681 -
Efficacy Trial of Intracranial Aneurysm Treatment Using Two Different Endovascular Techniques
|
N/A | |
Completed |
NCT00396981 -
MAPS Trial: Matrix And Platinum Science
|
Phase 4 | |
Completed |
NCT02921711 -
TRAIL: Treatment of Intracranial Aneurysms With LVIS® System
|
||
Recruiting |
NCT05636124 -
Kaneka iED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms
|
N/A | |
Completed |
NCT02921698 -
Safety and Efficacy Analysis of FRED® Embolic Device in Aneurysm Treatment
|
||
Completed |
NCT01793792 -
Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)
|
N/A | |
Terminated |
NCT01974700 -
Seizure Prophylaxis in Aneurysm Repair
|
Phase 4 | |
Completed |
NCT01801007 -
Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms
|
N/A |