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Intracranial Aneurysms clinical trials

View clinical trials related to Intracranial Aneurysms.

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NCT ID: NCT01945827 Withdrawn - Clinical trials for Intracranial Aneurysms

Evaluation of DeltaMaxx® Microcoil System in Intracranial Aneurysms

Start date: January 2014
Phase: N/A
Study type: Observational [Patient Registry]

The primary objective of this registry is to assess the safety and angiographic outcomes of endovascular treatment of intracranial aneurysms using the DeltaMaxx Microcoil System.

NCT ID: NCT01801072 Completed - Clinical trials for Intracranial Aneurysms

Seizure Prophylaxis in Aneurysm Repair

SPAR
Start date: February 2013
Phase: Phase 4
Study type: Interventional

After a thorough review of the existing literature as well as a review of our own practice, the investigators have concluded that the decision to treat patients undergoing aneurysm repair with levetiracetam has reached true clinical equipoise. In other words, the investigators cannot favor a decision to either administer or not administer this drug in these patients based on the existing information. The utility of anti-epileptic prophlaxis in the perioperative period for patients undergoing intracranial aneurysm repair remains a common practice that is not supported by the current literature that includes retrospective analyses as well as prospective trials for similar but not identical types of patients. The investigators propose to settle this dilemma by performing a prospective randomized trial in patients undergoing aneurysm repair in order to definitively determine if the common practice of perioperative antiepileptic drug administration has any utility. The study will be extended to June 2024 to allow for a 5 year follow up of the last enrolled patient in June, 2019.

NCT ID: NCT01801007 Completed - Clinical trials for Intracranial Aneurysms

Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms

FRED
Start date: July 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of the MicroVention Flow Redirection Intraluminal Device (FRED) system when used in the treatment of wide-necked intracranial aneurysms.

NCT ID: NCT01793792 Completed - Clinical trials for Intracranial Aneurysms

Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)

LVIS
Start date: July 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the Low Profile Visualized Intraluminal Support(LVIS™ and LVIS™ Jr.)devices from MicroVention, Inc. when used to facilitate endovascular coiling of wide-necked intracranial aneurysms with coils.

NCT ID: NCT01754051 Completed - Clinical trials for Intracranial Aneurysms

A Volumetric Coiling in Aneurysm Registry of the Penumbra Coil 400TM System

VOLCAN
Start date: January 2013
Phase:
Study type: Observational [Patient Registry]

This study is a prospective, multi-center registry of patients with intracranial aneurysms who are treated by the PC 400 System. Data for each patient are collected up to 12 ± 3 months post-procedure for the study.

NCT ID: NCT01748903 Recruiting - Clinical trials for Intracranial Aneurysms

TARGET Intracranial Aneurysm Coiling Registry

TARGET
Start date: February 2013
Phase:
Study type: Observational [Patient Registry]

The purpose of this prospective registry is to collect real world, post-marketing data on the use of Stryker Target® 360,Target® 2D, and 2nd generation Target® Nano coils for the embolization of ruptured or unruptured intracranial saccular aneurysms. Up to 300 patients (150 in the TARGET 360°/Helical arm and 150 in the New NANO arm) presenting with intracranial aneurysms suitable for coil embolization will be enrolled at up to 20 sites. A post hoc analysis comparing Target® 360° and Target® 2D coil technical and clinical endpoints will be performed.

NCT ID: NCT01722409 Completed - Clinical trials for Intracranial Aneurysms

A Better Choice for Patients Undergoing Endovascular Coil Embolization

Start date: December 2012
Phase: Phase 4
Study type: Interventional

The investigators designed a double-blind, randomized placebo-controlled study to determine the effects of dexmedetomidine on the recovery characteristics of patients who were scheduled to undergo endovascular coil embolization.

NCT ID: NCT01541254 Completed - Clinical trials for Intracranial Aneurysms

Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device

LVIS
Start date: March 2012
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and probable benefit of the Low-profile Visualized Intraluminal Support (LVIS™ and LVIS™ Jr.)devices from MicroVention, Inc. when used to facilitate endovascular coiling of unruptured wide-neck intracranial aneurysms with bare platinum embolization coils.

NCT ID: NCT01465841 Completed - Clinical trials for Intracranial Aneurysms

Study of the Penumbra Coil 400 System to Treat Aneurysm

ACE
Start date: November 2011
Phase: N/A
Study type: Interventional

This is a prospective, multi-center study of patients with intracranial or peripheral aneurysms who are treated by the PC 400 System. The primary objective is to gather post market data on the Penumbra Coil 400 (PC 400) System in the acute treatment of intracranial and peripheral aneurysms. Approximately 2,000 patients with intracranial or peripheral aneurysms treated by the PC 400 System at up to 100 centers will be enrolled. Data for each patient are collected up to discharge or 3 days post-procedure, whichever occurs sooner. Long term follow-up to one year will be conducted in accordance to the standard of care at each participating hospital.

NCT ID: NCT01320306 Terminated - Clinical trials for Intracranial Aneurysms

Intracranial Aneurysms and Cognitive Function

Start date: March 2011
Phase:
Study type: Observational

The prevalence rate of intracranial aneurysms in the adult population is close to 5%. Rupture risk of such aneurysms causing subarachnoid hemorrhage (SAH) can be substantial.Most patients suffering from an aneurysmal SAH are in their mid life, i.e., 30 to 60 years old. Aneurysmal SAH may cause disability and mortality. The present study includes a follow-up study and a cross-sectional fMRI study. The purpose of the follow-up study is to monitor patients receiving prophylactic surgical treatment of their un-ruptured aneurysms to examine whether such treatment is associated with cognitive, psychosocial and/or neurologic sequela. The purpose of the cross-sectional fMRI study is to examine the relationship between memory function and brain activity among SAH patients. Memory impairment is often found among aneurysmal SAH patients. Using fMRI can possibly shed some light on whether such memory impairment may be caused by diffuse cerebral damage or a focal damage at the aneurysm site.