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A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients — MACH  

Intracerebral Hemorrhage Clinical Trial

Official title:
Minocycline in Acute Cerebral Hemorrhage (MACH) Trial

Clinical Trial Summary

The MACH Trial is a pilot study of 400mg minocycline over five days in acute intracerebral hemorrhage patients. The study will evaluation the safety and efficacy of minocycline in intracerebral hemorrhage patients.

Clinical Trial Description

MACH is a randomized trial of minocycline in intracerebral hemorrhage. 24 total subjects will be randomly assigned to minocycline or control (1:1). The first dose will be given intravenously. Subsequent doses will be given orally every 24 hours for a total of five doses. The study will test to see if the medication is safe in intracerebral hemorrhage. The pharmacokinetics of minocycline in intracerebral hemorrhage will be determined and the impact of minocycline on blood biomarkers. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01805895
Study type Interventional
Source Augusta University
Contact
Status Completed
Phase Phase 1/Phase 2
Start date February 2013
Completion date December 2016
View Details
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