Platelet Transfusion in Acute Intracerebral Hemorrhage

Intracerebral Hemorrhage Clinical Trial

Official title: Platelet Transfusion in Acute Primary Intracerebral Hemorrhage for Patients on Platelet Inhibitors

Status Recruiting

Clinical Trial Summary

• To prove whether use of antiplatelet agents results into a rapid enlargement of hematoma after onset of acute intracerebral hemorrhage.

• To prove the efficacy and safety of platelet transfusion for prevention of hematoma growth in patients who were stricken by acute intracerebral hemorrhage while being on antiplatelet medication.

Clinical Trial Description

• Hematoma growth is a well-known powerful determinant of mortality and poor outcome after intracerebral hemorrhage.

• Some observations suggest that previous use of antiplatelet agents associates with rapid hematoma enlargement and poor outcome after cerebral hemorrhage.

• Immediate platelet transfusion for such patients may prevent hematoma growth but also cause thromboembolic complications. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Cerebral Hemorrhage
• Hemorrhage
• Intracerebral Hemorrhage

• NCT number: NCT00699621
• Study type: Interventional
• Source: University of Oulu
• Contact: Matti E Hillbom, MD, PhD
• Phone: 358-8-315-4518
• Email: matti.hillbom@oulu.fi
• Status: Recruiting
• Phase: N/A
• Start date: January 2009
• Completion date: December 2014