Intracerebral Hemorrhage Clinical Trial
Official title:
A Double-blind Randomized Trial to Compare the Efficacy of Intermittent Pneumatic Compression (IPC) With and Without Early Anticoagulant Treatment for Prevention of Venous Thromboembolism (VTE) in Patients With Acute Primary Intracerebral Hemorrhage (ICH)
- To evaluate the efficacy of using IPC during the acute phase of ICH in the prevention
of VTE.
- To assess the safety and efficacy of additional therapy with enoxaparin.
- To compare the efficacy and safety of the European and American guideline
recommendations.
- To provide an efficient and safe thromboprophylaxis for several weeks until the patient
is able to walk.
- Although it has been poorly investigated, the risk of VTE among patients with acute
primary intracerebral hemorrhage is generally believed to be at least as high as among
patients with ischemic stroke.
- The currently available guidelines state that while low doses of subcutaneous heparin
or low-molecular-weight heparin may reduce VTE, it is possible that their effect is
counterbalanced by an increase in hemorrhagic complications.
- It is still unclear when (if ever) low-molecular-weight-heparin should be safely
initiated in ICH patients.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
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