Clinical Trials Logo

Intrabony Periodontal Defect clinical trials

View clinical trials related to Intrabony Periodontal Defect.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT06371027 Completed - Clinical trials for Intrabony Periodontal Defect

Novel Silk Fibroin Nanofiber Membrane Using Minimally Invasive Surgery in Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Clinically and radiographically by cone beam CT evaluate the regenerative potentials of silk fibroin (SF) nanofiber membrane, using minimally invasive surgery, for the regenerative treatment of intrabony periodontal defects.

NCT ID: NCT05456555 Completed - Clinical trials for Intrabony Periodontal Defect

The Flapless Approach in Periodontal Regeneration

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The present investigation is designed in order to compare the radiographic and clinical effectiveness of flapless procedure performed alone or in combination with enamel matrix derivatives in the periodontal regenerative treatment of deep intrabony defects in patients with moderate or severe periodontitis. The study will have a follow-up of 12 months.

NCT ID: NCT04896450 Completed - Clinical trials for Intrabony Periodontal Defect

Comparison of the GTR Procedure Alone and in Combination With Immediate OTM

Start date: September 2015
Phase: N/A
Study type: Interventional

The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a GTR procedure, when it is combined with an immediate orthodontic tooth movement or used alone. Clinical, radiological and reentry (histological) evaluation of a regenerative surgical method (GTR + grafting material) with different postsurgical healing patterns in the treatment of wide, non-containing intrabony defects.

NCT ID: NCT04767243 Completed - Clinical trials for Chronic Periodontitis

Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®).

Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate and compare the regenerative potential of Advanced Platelet Rich Fibrin (A-PRF) and Bioactive Glass (Perioglas®) bone graft in the treatment of intrabony defects in chronic periodontitis patients.

NCT ID: NCT04698317 Completed - Clinical trials for Chronic Periodontitis

Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial

RCT
Start date: January 1, 2021
Phase: Phase 2
Study type: Interventional

This clinical study aimed to evaluate the efficacy of biodegradable gelatin sponge loaded with Beta-tricalcium phosphate socked in concentrated growth factors in the treatment of periodontal intra-bony defects, as compared with biodegradable gelatin/beta-tricalcium phosphate sponges alone.

NCT ID: NCT04319770 Completed - Clinical trials for Intrabony Periodontal Defect

Effectiveness of Hyaluronic Acid in the Regeneration of Infrabony Defects

Start date: September 6, 2016
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled clinical trial (RCT) is to determine the efficacy hyaluronic acid (HA) versus enamel matrix derivatives (EMD) in the treatment of infrabony periodontal defects.

NCT ID: NCT04100798 Completed - Clinical trials for Intrabony Periodontal Defect

Clinical and Radiographic Evaluation of the Entire Papilla Preservation (EPP) Technique Versus Modified Minimally Invasive Surgical Technique (M-MIST) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical Trial

Start date: February 8, 2020
Phase: N/A
Study type: Interventional

Periodontitis is defined as loss of periodontal attachment due to microbial associated host mediated inflammation. This would lead to the apical migration of the junctional epithelium allowing the bacterial biofilm to undergo apical widespread along the root surfaces of teeth causing bone resorption (Tonetti, Greenwell, & Kornman, 2018). The main objective of periodontal surgeries is directed at complete preservation of the interdental soft tissues to achieve primary closure over the intraosseous defected sites during the early phases of wound healing. Evidence shows that surgical techniques are highly predictable in the treatment of pockets associated with deep and shallow intrabony defects affected majorly by the selected flap design. The purpose of the flap design of minimally invasive periodontal surgery is to overcome the drawbacks of conventional periodontal surgeries decreasing the surgical trauma, improving the clot stability, reducing patient discomfort post operatively and minimizing the surgical chair time (Aslan, Buduneli, & Cortellini, 2017b) Modified Minimally Invasive Surgical Technique (M-MIST) is considered one of the latest minimally invasive techniques that have been used in the treatment of intraosseous defects, this technique however entails an incision over the defect-associated interdental papilla that may jeopardize the volume and complex vascular integrity of the interdental tissues, lacking the special flap design that would emphasis clot stability for better wound healing. Where a new surgical technique turned entire papilla preservation has been developed for protection of the wound without affecting the vascularity of the area. (Pierpaolo Cortellini & Tonetti, 2015) This randomized clinical trial compared the clinical and radiographic efficacy of entire papilla preservation surgical technique (EPP) to Modified minimally invasive surgical technique (M-MIST) in the treatment of periodontal intraosseous defects in stage III periodontitis patients.

NCT ID: NCT03924336 Completed - Clinical trials for Intrabony Periodontal Defect

The Effect of A-PRF+ Versus Open Flap Debridement in the Treatment of Patients With Stage III Periodontitis

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

To assess the effectiveness of advanced PRF+ as compared to open flap debridement in treatment of periodontal intraosseous defects in stage III periodontitis patients.

NCT ID: NCT03769402 Completed - Clinical trials for Intrabony Periodontal Defect

The Influence of Citric Acid Bone Surface Etching and Bone Defect Fill on GCF BMP-2 Release Profile

Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

This study evaluates the effect of citric acid on bone surface of infrabony defects when used for 30 seconds at ph 1 and 50% concentration before the application of bovine derived xenograft to fill the defect, Bone Morphogenic protein 2 (BMP-2) marker was evaluated in 5 different days during the first month after surgery and clinical and radiographic parameters were reassessed after 6 months

NCT ID: NCT03651908 Completed - Clinical trials for Intrabony Periodontal Defect

Comparison Between Bioactive Silica Graft Plus Platelet Rich Fibrin and Only Platelet Rich Fibrin Graft in Intrabony Defects With Diabetes

CBBSGPPOPIDWD
Start date: September 5, 2017
Phase: N/A
Study type: Interventional

Various regenerative procedures used for the treatment of intabony defects.The Aim of this study is to compare the treatment outcome of bioactive silica graft with platelet rich fibrin Vs bioactive silica graft in the treatment of intrabony defects in patients with diabetes mellitus.