Different Intra-abdominal Pressures and Optic Nerve Size

Intraabdominal Hypertension Clinical Trial

Official title:

Investigation of the Effects of Different Intra-abdominal Pressures on Optic Nerve Size Measured by Orbital USG in Patients Undergoing Major Abdominal Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04556877
• Other study ID #: TUTF 2018/230
• Status: Completed
• Start date: June 15, 2018
• Est. completion date: June 15, 2020

Study information

• Verified date: September 2020
• Source: Trakya University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Description:

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. This situation creates ischemia in the abdominal organs in the patient, decreases venous return as a result of inferior vena cava compression and leads to a decrease in cardiac output. In addition, intracranial pressure frequently increases as a result of the venous circulation being affected. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 78
• Est. completion date: June 15, 2020
• Est. primary completion date: June 15, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

Having had major abdominal surgery

Exclusion Criteria:

1. pregnant patients

2. Patients whose bladder catheter cannot be inserted

3. Patients with diagnosed or suspected brain death

Related Conditions & MeSH terms

• Intra-Abdominal Hypertension
• Intraabdominal Hypertension
• Major Surgery
• Optic Nerve Congestion

Intervention

Procedure:
• Intraabdominal pressure and optic nerve diameters
Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG

Locations

Country	Name	City	State
Turkey	Trakya University	Edirne

Sponsors (1)

Lead Sponsor	Collaborator
Trakya University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	optic nerve diameter	measuring optic nerve diameter	within 2 hours of admission
Primary	optic nerve diameter	measuring optic nerve diameter	at 6.hour
Primary	optic nerve diameter	measuring optic nerve diameter	at 12.hour
Primary	optic nerve diameter	measuring optic nerve diameter	at 24.hour