Clinical Trials Logo

Clinical Trial Summary

Intestinal obstruction is a common clinical problem that occurs secondary to mechanical or functional obstruction of the intestine, preventing normal transit of its contents. It is a frequent cause of hospitalization and represents 15-20% of surgical admissions for acute abdominal pain . The underlying aetiology of large bowel obstructions (LBOs) is age dependent, but in adulthood, the most common cause is colonic cancer (50-60%), typically in the sigmoid. The second most common cause in adults is acute diverticulitis (involving the sigmoid colon). Together, obstructing tumors and acute diverticulitis account for 90% of all causes of LBO. Adhesions are the most common cause of small bowel obstruction (SBO) , For practical purposes, they do not tend to cause LBO.Other causes which cause symptoms that are mimic intestinal obstruction as in bowel ischemia that mainly caused by mesenteric vessels occlusion (adynamic obstruction). Computed tomography (CT) has become a mainstay in diagnosing bowel obstruction. This is because the management of obstruction has dramatically changed with a decrease in the proportion of patients who need surgery Multi Detector Computed Tomography scanners provide a huge gain in performance that can be used to reduce the scan time, reduce section collimation, or to increase scan length surgery. Diagnosis of intestinal obstruction is established by patient history and clinical findings include abdominal distension, acute abdominal pain, vomiting and inability to pass stools or flatus . The role of CT in diagnosing intestinal obstruction has been expanding by determining presence, degree, level and cause (extrinsic lesions, intrinsic lesions, intussusception, intraluminal lesions) of obstruction and in identifying any associated strangulation, and also it has an important role in diagnosing the mesenteric vessels obstruction by thrombi by injection of IV contrast media which causes adynamic bowel obstruction .

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05117645
Study type Observational
Source Sohag University
Contact Alaa N Abd El ghafar, resident
Phone 01063550892
Email [email protected]
Status Not yet recruiting
Start date December 2021
Completion date June 2022

See also
  Status Clinical Trial Phase
Completed NCT00332696 - Octreotide Compared to Placebo in Patients With Inoperable Bowel Obstruction Due to Peritoneal Carcinomatosis Phase 2
Completed NCT00216372 - Efficacy and Safety of Lanreotide Microparticles as Palliative Treatment in Peritoneal Carcinomatosis Phase 3
Withdrawn NCT02928458 - Clinical and Financial Impact of an Evidenced-Based Adhesive Small Bowel Obstruction Management Protocol N/A
Completed NCT00758186 - Randomized Trial of Colonic Stents as a Bridge to Surgery Phase 3
Completed NCT02275338 - Study to Assess Efficacy and Safety of Lanreotide Autogel 120 MG in Treatment of Clinical Symptoms Associated With Inoperable Malignant Intestinal Obstruction Phase 2
Completed NCT03997721 - Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy
Recruiting NCT01669044 - Comparison the Hemodynamics Effects Between Dexmedetomidine and Propofol in Major Abdominal Surgical Patients N/A
Completed NCT01596764 - Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time. Phase 1
Completed NCT04020939 - The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. N/A
Completed NCT01899885 - Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course N/A
Completed NCT00130715 - Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery N/A
Not yet recruiting NCT01125280 - Prospective Multicenter Validation of a Severity Score of Strangulated Small Bowel Occlusion N/A
Terminated NCT02365584 - Quality of Life in Patients With Inoperable Malignant Bowel Obstruction Phase 2
Completed NCT01596777 - Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects Phase 1
Not yet recruiting NCT04213976 - Ostomy in Continuity or Conventional Ileostomy: a Retrospective Multicentric Analysis
Completed NCT03663023 - Band Adhesions in Relation to Previous Abdominal Surgery - a Retrospective Analysis of Risk Factors
Recruiting NCT03773237 - Intralipid Versus SMOFlipid in HPN Patients N/A
Recruiting NCT04403425 - Tissue Perfusion During Emergency Laparotomy
Terminated NCT01196494 - Study of Intraoperative Colonic Irrigation Versus Stent Placement in Obstructive Left-Sided Colonic Cancer N/A