Intestinal Metaplasia Clinical Trial
Official title:
Endoscopic Radiofrequency Ablation for Gastric Metaplasia and Dysplasia
Gastric intestinal metaplasia (IM) and dysplasia, also referred to as intra-epithelial
neoplasia, are well recognized precursors of gastric cancer. Apart from endoscopic
surveillance, there is no other intervention which predictably eradicates pre-cancerous
gastric lesions.
Endoscopic radiofrequency ablative (RFA) therapy has been recently shown to be highly
effective in eradicating both IM and dysplasia in patients with Barrett's esophagus.
However, the potential role of RFA to remove gastric IM and dysplasia remains unknown. In
this study, we determine the feasibility of using endoscopic RFA in treating early gastric
neoplasia (metaplasia and dysplasia). Patients with gastric metaplasia and/or dysplasia will
be treated with endoscopic RFA. The safety and effects of RFA will be determined.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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