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Intestinal Diseases clinical trials

View clinical trials related to Intestinal Diseases.

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NCT ID: NCT05176366 Recruiting - Ulcerative Colitis Clinical Trials

Study of ExoFlo for the Treatment of Medically Refractory Ulcerative Colitis

Start date: December 19, 2022
Phase: Phase 1
Study type: Interventional

Protocol Summary - Title: A Phase I study of ExoFlo, an ex vivo culture-expanded adult allogeneic bone marrow mesenchymal stem cell derived extracellular vesicle isolate product, for the treatment of medically refractory ulcerative colitis. - Short Title: ExoFlo for ulcerative colitis - Phase: 1 - Methodology: Open label - Study Duration: 24 months - Subject Participation: 58 weeks - Single or Multi-Site: Multi-Site

NCT ID: NCT05176327 Recruiting - Clinical trials for Spinal Cord Injuries

Exoskeleton Neurogenic Bowel Dysfunction Study

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the effects of exoskeleton training on neurogenic bowel disorders in spinal cord injury/ disease.

NCT ID: NCT05174754 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Response To Medical Therapy in Inflammatory Bowel Disease Patients Carrying-out a Prescribed Exercise Programme

Start date: August 30, 2022
Phase: N/A
Study type: Interventional

The investigators propose the use of a 20 week physician-derived exercise programme will lead to an improvement in physical fitness which will in turn lead to an increase in muscle mass, a reduction in visceral obesity resulting in an improvement in biologic response, disease biomarkers (including a reduction in circulating pro-inflammatory cytokines), fatigue scores and quality of life.

NCT ID: NCT05159921 Recruiting - Clinical trials for Gastro-Intestinal Disorder

Can the SurgInfoBot Improve the Consent Process for Endoscopy? A Randomised Controlled Trial

Start date: November 29, 2021
Phase: N/A
Study type: Interventional

Human-computer interactions or 'Chatbots' have been utilized in a variety of healthcare settings, including the promotion of positive healthcare behaviors, the deliverance of psychological therapy, and the performance of diagnostic tasks. Standard methods of consenting patients for procedures may not always result in patients being fully informed; a 2004 study of patients undergoing screening sigmoidoscopy demonstrated that 39% of surveyed patients could describe no other indication than doctor recommendation for the procedure after undergoing standard consent. his study seeks to investigate the usability of a novel chatbot designed to provide peri-procedural information in two endoscopic procedures - diagnostic oesophagogastroduodenoscopy (OGD) and diagnostic colonoscopy. A novel Chatbot - 'SurgInfoBot' has been developed in order to provide real-time, patient-driven peri-procedural information. This study primarily seeks to assess the effect of SurgInfoBot use on patient satisfaction with the consent process in endoscopy. It will also assess the usability of the chatbot according to the system usability scale and test performance according to the as-yet unvalidated Chatbot Usability Questionnaire (CUX). User engagement will be analyzed objectively using stored metrics. Comparison will be made between perceptions of the SurgInfoBot as an information source and other established patient information sources. The potential impact of the SurgInfoBot on peri-procedural anxiety will also be explored.

NCT ID: NCT05130983 Recruiting - Crohn Disease Clinical Trials

Study of ExoFlo for the Treatment of Medically Refractory Crohn's Disease

Start date: January 23, 2023
Phase: Phase 1
Study type: Interventional

Protocol Summary - Title: A Phase I study of ExoFlo, an ex vivo culture-expanded adult allogeneic bone marrow mesenchymal stem cell derived extracellular vesicle isolate product, for the treatment of medically refractory Crohn's disease. - Short Title: ExoFlo for Crohn's Disease - Phase: 1 - Methodology: Open label - Study Duration: 24 months - Subject Participation: 58 weeks - Single or Multi-Site: Multi-Site

NCT ID: NCT05079932 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Pilot Study for the Evaluation of Food Choices in Patients With Inflammatory Bowel Diseases (MICI2021)

MICI2021
Start date: April 1, 2021
Phase:
Study type: Observational

This project is a pilot study exploring the effects of dietary choices and quantitative digestion of gluten ingested by individuals with IBD compared to a control population. The aim of the study is to evaluate for the first time in an Italian population of subjects with IBD the presence of a diet based on GFD (gluten free diet).

NCT ID: NCT05071742 Recruiting - Clinical trials for Inflammatory Bowel Disease

Correlation of Genetic Susceptibility Genes to Inflammatory Bowel Disease in Chinese Han Population

CGSGIBDCHP
Start date: November 25, 2021
Phase:
Study type: Observational

The pathogenesis of IBD is still unclear, and the disease characteristics of IBD patients are affected by genetic susceptibility genes. Therefore, this study aims to explore the relationship between genetic susceptibility genes of IBD and the pathogenesis of IBD in Chinese Han population, in order to clarify the pathogenesis of IBD and provide basis for individualized treatment of IBD.

NCT ID: NCT05069233 Recruiting - Stomach Diseases Clinical Trials

Magnetically Controlled Capsule Endoscopy in Visualization of the UGI and Small Intestine

Start date: September 27, 2021
Phase:
Study type: Observational

In this study, we retrospectively analyzed the videos of combined upper digestive tract and small intestine examination under MCE, so as to clarify the feasibility and diagnostic efficacy of MCE in one-time examination of the upper gastrointestinal and small intestinal mucosa.

NCT ID: NCT05040854 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Can we Rely on HLA to Predict Resistance to Biological Therapy in IBD Patients

Start date: July 1, 2021
Phase:
Study type: Observational

The investigators propose an observational study including patients with inflammatory bowel disease under biological therapy with anti-TNF, anti-integrin α₄β₇ or anti-interleukin 12-23 (Ustekinumab), followed by an external Gastroenterology consultation at Centro Hospitalar Tondela-Viseu.

NCT ID: NCT05004207 Recruiting - Clinical trials for Irritable Bowel Syndrome

Study of Oro-cecal Transit Time in Healthy Subjects Using Scintigraphy and Lactulose Hydrogen Breath Test.

Start date: July 1, 2021
Phase:
Study type: Observational

Radionuclide scintigraphy is the gold standard technique to interpret OCTT but there is no normative data available for its interpretation in Indian population. Previous studies to determine OCTT have all been done with LHBT, which has many limitations. Besides there are few small comparative studies between scintigraphy and LHBT, that too not in Indian population. The aim of this study is to validate LHBT to measure OCTT compared with scintigraphy and to standardize the normal OCTT in healthy individuals