Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery

Intervertebral Disc Prolapse Clinical Trial

Official title: Gabapentin vs. Pregabalin for Post Operative Pain in Lumbar Microdiscectomy: a Randomized Controlled Trial.

Status Completed

Clinical Trial Summary

Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery.

The investigators found that pregabalin is equivalent to gabapentin for relief of post-operative pain at a lower dose in patients undergoing intervertebral disc surgery.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Intervertebral Disc Displacement
• Intervertebral Disc Prolapse

• NCT number: NCT02120703
• Study type: Interventional
• Source: Aga Khan University
• Status: Completed
• Phase: Phase 3
• Start date: February 2011
• Completion date: October 2011