Intervertebral Disc Herniation Clinical Trial
Official title:
Evaluating Changes in Mechanical Properties in the Herniated Intervertebral Disc
Low back pain is a major cause of disability, especially in the working-age population. A total of 149 million working days are lost every year as a consequence of back pain. Intervertebral disc (IVD) degeneration is thought to play a major role in chronic back and neck pain. Decades of bench-top research in tissue mechanics have shown clear relationships between changes in mechanical properties and abnormal changes IVD structure and composition. Our overall hypothesis is that measurements of IVD mechanical properties can provide valuable information about its structure and composition for early diagnosis of degeneration, quantification of degeneration progress, and evaluation of treatment strategies. Magnetic Resonance Elastography (MRE) is an imaging method to quantify mechanical properties from soft tissues. The objectives of this study are to evaluating repeatability and collecting base line data from healthy individuals; and to apply MRE to patients with disc herniation.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03158766 -
Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID)
|
||
| Completed |
NCT05296200 -
Cervical Changes by 4h of Hyper-buoyancy Flotation and Followed by 15 Mins 1g Re-loading
|
||
| Recruiting |
NCT02257723 -
The Effect of Integrated CAM Treatment in Hospitalized Patients
|
||
| Active, not recruiting |
NCT04254250 -
Preoperative Estimation Of Disc Herniation Recurrence In Patients With Lumbar Disc Herniation
|
||
| Completed |
NCT02742311 -
EuroPainClinics® Study V (Prospective Observational Study)
|
N/A |