Sciatica Clinical Trial
Official title:
Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation: a Three-armed, Randomized, Double-blind Controlled Pilot Study
This trial will evaluate the comparative clinical effectiveness of pharmacopuncture for severe non-acute sciatic pain patients diagnosed with lumbar disc herniation (LDH) with usual care of conventional medicine and that of Korean medicine (acupuncture). Sixty patients with severe non-acute sciatic pain patients diagnosed with LDH (NRS ≥5, 4 weeks - 6 months) will be recruited, and randomized 20 each to the Shinbaro pharmacopuncture, acupuncture, and usual care group, respectively. The 2 acupuncture groups will receive 2 sessions/week of acupuncture alone or with pharmacopuncture for 4 weeks, and the usual care group will receive conventional medication 2 times/day and 2 sessions/week of physical therapy. Post-treatment evaluations will take place 5, 7, 9, and 12 weeks after randomization.
This study is a three-armed, randomized, patient, physician, and assessor-blinded, controlled pilot to the aim of evaluating the comparative clinical effectiveness of pharmacopuncture for severe non-acute sciatic pain patients diagnosed with lumbar disc herniation (LDH) with usual care of conventional medicine and that of Korean medicine (acupuncture). Sixty patients with severe non-acute sciatic pain patients diagnosed with LDH (NRS ≥5, onset between 4 weeks and 6 months) will be recruited, and randomized 20 each to the Shinbaro pharmacopuncture (pharmacopuncture+acupuncture), acupuncture, and usual care group, respectively. The 2 acupuncture groups will receive 2 sessions/week of acupuncture alone or with pharmacopuncture for 4 weeks (total 8 sessions), and the usual care group will receive conventional medication 2 times/day and 2 sessions/week of physical therapy (total 8 sessions). The initial acupuncture physician will administer acupuncture at 5 acupoints (GB30, BL40, BL25, BL23, GB34) in the 2 acupuncture groups, and mark an additional acupoint. A second acupuncture physician will administer pharmacopuncture to the marked acupoint in the pharmacopuncture group, and acupuncture in the acupuncture group. Post-treatment evaluations will take place 5, 7, 9, and 12 weeks after randomization. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05626140 -
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
|
Phase 3 | |
Withdrawn |
NCT02313350 -
Intradiscal Discogel® in Resistant Sciatica
|
N/A | |
Unknown status |
NCT02512081 -
"The Lived Experience of Investigations for Sciatica"
|
N/A | |
Recruiting |
NCT06179901 -
The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents
|
N/A | |
Terminated |
NCT02951377 -
Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy
|
Phase 1 | |
Completed |
NCT03347929 -
NSAIDs in Sciatica NSAIDS IN SCIATICA
|
Phase 4 | |
Completed |
NCT04145310 -
BOL-DP-o-04 in Patients With Low Back Pain and Sciatica
|
Phase 1/Phase 2 | |
Enrolling by invitation |
NCT04660656 -
Predictive Value of the Five-repetition Sit-to-stand Test After Lumbar Spine surgerySTS-3 Study.
|
||
Completed |
NCT02644421 -
Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
|
Phase 1 | |
Completed |
NCT00991172 -
A Study to Evaluate the Safety and Efficacy of Subcutaneously Administered REGN475(SAR164877) in Patients With Sciatic Pain
|
Phase 2 | |
Completed |
NCT00668434 -
Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica
|
Phase 2 | |
Completed |
NCT00749996 -
Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease
|
Phase 4 | |
Completed |
NCT00246948 -
The Efficacy of Active Conservative Treatment for Patients With Severe Sciatica. A Randomized Clinical Controlled Trial
|
N/A | |
Completed |
NCT04155450 -
Effects of Extension Biased External Limb Loading in Addition to McKenzie Extension Protocol in Lumbar Derangement Syndrome
|
N/A | |
Completed |
NCT02284542 -
NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators
|
||
Recruiting |
NCT02770963 -
Efficacy of Acupuncture for Discogenic Sciatica
|
N/A | |
Completed |
NCT00364572 -
Efficacy of Epidural Etanercept in the Treatment of Sciatica
|
Phase 1/Phase 2 | |
Completed |
NCT00470509 -
Adalimumab in Severe and Acute Sciatica
|
Phase 2 | |
Active, not recruiting |
NCT03887962 -
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
|
N/A | |
Completed |
NCT05959317 -
Effects of Pilates Exercises and Neural Dynamic Mobilization in Sciatica Patients
|
N/A |