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Intervertebral Disc Displacement clinical trials

View clinical trials related to Intervertebral Disc Displacement.

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NCT ID: NCT04042844 Recruiting - Lumbar Disc Disease Clinical Trials

A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

Start date: June 30, 2022
Phase: Phase 2
Study type: Interventional

This is a double-blind, saline-controlled, and randomized study with blinded assessments using a single dose. Subjects that have a current diagnosis of chronic lumbar disc disease and meet eligibility criteria will be enrolled. Chronic lumbar disc disease is defined as back and/or radicular pain with degeneration of the disc confirmed by patient history, physical examination, and radiographic measures such as computed tomography (CT), magnetic resonance imaging (MRI), plain film, myelography, discography, or other acceptable means.

NCT ID: NCT04012996 Recruiting - Clinical trials for Symptomatic Cervical Disc Disease

2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C

SMART
Start date: August 5, 2019
Phase: N/A
Study type: Interventional

A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).

NCT ID: NCT03745040 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion

Start date: January 26, 2019
Phase: Phase 4
Study type: Interventional

This study will describe postoperative pain management for spine surgery patients receiving liposomal bupivacaine (Exparel®) compared to patients not receiving the drug.

NCT ID: NCT03475095 Recruiting - Low Back Pain Clinical Trials

Motor Control Mechanisms by CNS of Tuina in Patients With Lumbar Disk Herniation

Start date: March 10, 2018
Phase: N/A
Study type: Interventional

Lumbar disk herniation (LDH)is a prevalent health problem around the world. It can cause symptoms of low back pain, numbness or weakness.The understanding of low back pain in traditional Chinese medicine(TCM) theory"unbalanced bones and muscles"that is consistent with the description of modern medicine on LDH function pathology. Tuina is one of Diagnosis and treatment methods in TCM which has been used as a noninvasive treatment of LDH. However, the mechanism of Tuina therapy in LDH is still unclear.The purpose of this study is to establish a platform of the therapeutic effect and mechanical effect of LDH in the treatment of LDH,explore the characteristics of Tuina by the motor control in lumbar CNS,observe the patterns and regularities in the function of related brain regionin of patients with acute or chronic LDH and reveal the mechanism of Tuina of improving the control of lumbar spine CNS movement.

NCT ID: NCT03453775 Recruiting - Low Back Pain Clinical Trials

Ultrasound-guided Lumbar Periradicular Injection: a Non Irradiating Infiltration Technique

Start date: February 27, 2018
Phase: N/A
Study type: Interventional

We propose here to evaluate the precision of lumbar periradicular infiltration performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position. The effectiveness of the technique will be assessed by measuring different pain and disability scores at four weeks post-infiltration: the Visual analogue pain Scale score, the DN4 score, and the Oswestry disability score (ODI); The decrease in irradiation received will be collected, compared to that of the conventional fluoroscopic technique.

NCT ID: NCT03403244 Recruiting - Clinical trials for Lumbar Herniated Disc

US-MR Image Fusion-guided Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc Herniation

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility and efficacy of US-MR image fusion-guided percutaneous transforaminal endoscopic discectomy for the treatment of lumbar disc herniation

NCT ID: NCT03198273 Recruiting - Clinical trials for Lumbar Disc Herniation

The Efficacy of Clinical Pilates Exercises on Individuals With Lumbar Disc Herniation

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The aim of the study is to determine the effects of clinical Pilates Exercises on the level of pain, functional status, flexibility, static and dynamic endurance of the truncus muscles and quality of life in patients with lumbar disc herniation.

NCT ID: NCT03064802 Recruiting - Clinical trials for Degenerative Disc Disease

Burst Biologics Spinal Fusion Registry

Start date: March 24, 2017
Phase:
Study type: Observational [Patient Registry]

A multicenter patient registry was created with aim of documenting how spine and neurosurgeons are utilizing Burst Biologics products along with patient outcomes. These include radiographic measures such as fusion outcome, instrumentation integrity, and clinical outcomes (symptom and function improvement) based on surgeon and patient based outcome assessments.

NCT ID: NCT02936765 Recruiting - Clinical trials for Intervertebral Disc Displacement

Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Spacer Squale (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse

Start date: June 2016
Phase: N/A
Study type: Interventional

This is an investigator-initiated study. The primary goal is to evaluate the efficacy of two different cervical disc devices (prosthesis vs rigid spacer) with respect to postoperative change in neck disability index. The evaluation will include clinical and radiological parameters.

NCT ID: NCT02936739 Recruiting - Clinical trials for Intervertebral Disc Displacement

Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Prosthesis Rotaio (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse

Start date: June 2016
Phase: N/A
Study type: Interventional

This is an investigator-initiated study. The primary goal is to evaluate the efficacy of two different cervical disc prosthetic devices with respect to postoperative change in neck disability index. The evaluation will include clinical and radiological parameters.