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Intervertebral Disc Displacement clinical trials

View clinical trials related to Intervertebral Disc Displacement.

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NCT ID: NCT01997086 Active, not recruiting - Clinical trials for Lumbar Herniated Disc

Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation

Start date: October 2013
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of two minimal invasive endoscopic discectomy, PTED and MED, for the treatment of symptomatic lumbar disc herniation.

NCT ID: NCT01989403 Completed - Sciatica Clinical Trials

Alternative and Integrative Therapy for Lumbar Disk Herniation

Start date: February 2006
Phase:
Study type: Observational [Patient Registry]

The investigators report management of lumbar disc herniation with severe sciatic pain using an integrative complementary and alternative medicine approach with a 5 year follow-up.

NCT ID: NCT01970514 Active, not recruiting - Clinical trials for Lumbar Disc Prolapse With Radiculopathy

Safety Study of ARO Spinal System as an Adjunct to Lumbar Decompression

Start date: April 2012
Phase: Phase 0
Study type: Interventional

To evaluate the clinical safety and effectiveness of the ARO Spinal System and to assess preliminary cost/benefit analysis in patients undergoing decompression surgery for symptomatic lumbar disc herniations. The general hypothesis is that the ARO significantly improves outcomes in patients undergoing decompression surgery for symptomatic lumbar disc herniations.

NCT ID: NCT01944345 Completed - Clinical trials for Intervertebral Disc Degeneration

Patient Registry to Observe Outcomes Following Implantation of the VariLift Interbody Fusion Device

Start date: June 2013
Phase: N/A
Study type: Observational [Patient Registry]

The registry has been designed as a prospective, observational program for patients undergoing lumbar or cervical fusion using VariLift device with the ultimate goal to aid in the development of strategic treatment pathways and improved patient care. All patients who agree to participate in the registry will sign an informed consent form and subsequently be treated by their surgeon with the VariLift device. Potential treatment procedures include bilateral posterior lumbar interbody fusion (PLIF), unilateral transforaminal lumbar interbody fusion (TLIF), or bilateral anterior lumbar interbody fusion (ALIF) for the lumbar spine, or cervical unilateral or bilateral ACDF procedure. Surgical procedures can be performed in either an inpatient or outpatient facility. It is anticipated that the VariLift devices will improve patient outcomes and lead to the development of treatment pathways to improve patient care.

NCT ID: NCT01922063 Completed - Clinical trials for Intervertebral Disc Displacement

Physiotherapy Following Disc Surgery: Long Term Follow-up of a RCT

Start date: July 1996
Phase: Phase 3
Study type: Interventional

Hitherto no comprehensive long-term follow-up data of 10 years and more have been obtained from survivors of disc surgery that would have considered the type of postoperative care. Objectives: 1) To evaluate the long-term effects of postoperative comprehensive physiotherapy starting 1 week after lumbar disc surgery. 2) To assess the relative risk of segmental instability in the operated segment 12 years following lumbar disc surgery.

NCT ID: NCT01843296 Completed - Clinical trials for Lumbar Spine Disc Herniation

Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery

Start date: November 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to Compare three methods of intrathecal bupivacaine; bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and postoperative pain in patients undergoing lumbar disk herniation surgery.

NCT ID: NCT01824108 Completed - Clinical trials for Lumbar Disc Herniation

Wallis Interspinous Dynamic Stability System for Lumbar Disc Herniation: a Prospective Study

Start date: July 2008
Phase: Phase 3
Study type: Interventional

Lumbar disc herniation is usually treated by discectomy alone. Nonfusion system such as Wallis interspinous implants have also been successfully used in disc degenerative diseases. However, the superiority of a discectomy with Wallis in comparison to a discectomy alone for primary lumbar disc herniation has yet to be determined.The aim of our study is to investigate whether lumbar discectomy combined with the Wallis device provides better radiographic and clinical short-term outcome than posterior lumbar discectomy alone.

NCT ID: NCT01811251 Completed - Clinical trials for Patients Undergoing a Lumbar Slipped Disc Surgery

Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery

DEXA-PG-HD
Start date: December 2012
Phase: Phase 3
Study type: Interventional

The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, pregabalin, or a combination of these two products. Pain assessed by simple numerical scale will be also evaluated during the 48 first post-operative hours. Determining an optimal co-analgesic protocol through the results of this study could help develop validation studies with larger scale such as a medico-economic component. In addition, these study protocols are easy to apply (ponctual administration) and inexpensive.

NCT ID: NCT01808014 Recruiting - Clinical trials for Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc

The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery

Start date: February 2013
Phase: N/A
Study type: Interventional

Posterior lumbar spinal surgical pain leads to a severe degree of pain, and, hence, various means of pain management are required. Opioid pain medications such as morphine and fentanyl are frequently used as intravenously administered medications. To reduce the use of opioids for pain relief, a non-opioid form of pain relief, such as a Non-Steroidal Anti-Inflammatory Drug (NSAID), is often added to the regimen. With the use of NSAIDs, however, the risk of systemic side effects such as bleeding, gastroduodenal bleeding, and kidney damage are being reported, and there is also a report of inhibition of spinal fusion; these risks limit the use of NSAIDs. Nefopam, a new centrally-acting analgesic agent, has been reported in an animal study to desensitize post-surgical pain, and when used with an opioid analgesic, it indirectly controlled the NMDA receptor, which inhibited the generation of c-fos gene at the spine. There are also reports that Nefopam managed pain by inhibiting the serotonin reuptake receptors. In clinical practice, the administration of Nefopam in patients who required post-surgical pain management reduced the use of opioid analgesics by 20-50 % and also reduced the prevalence of nausea and vomiting. Therefore, the investigators considered whether the addition of Nefopam for intravenous patient-controlled analgesia in patients with lumbar spinal surgery would reduce the side effects seen in monotherapy with opioid analgesia and result in effective pain management. This study was conducted to address this question.

NCT ID: NCT01797172 Recruiting - Clinical trials for Contained Cervical Disc Herniation

Is Treatment of the Intervertebral Disc More Effective at Short-term Than the Nerve Root in Patients With a Neck Hernia?

Start date: October 2012
Phase: N/A
Study type: Interventional

Pain management in a neck hernia relies initially on rest, physiotherapy, and/or oral medications. Once these treatments have failed, different alternative procedures can be applied to relief pain. Thermal treatment of the intervertebral disc (Percutaneous Cervical Nucleoplasty; PCN) is the most often applied technique on the neck with a low risk of thermal damage. A variety of published studies have demonstrated this treatment to be both safe and effective. However, treatment of the nerve root (Pulsed Radio Frequency; PRF) is also a popular type of pain treatment. The application of PRF is also a safe and useful intervention for neck pain. Although these treatment types are described in the literature, the available evidence for efficacy is not sufficient to allow definitive conclusions on the optimal therapy to be made. The purpose of this study is to investigate which technique is the most effective in terms of pain relief on short term in patients with contained cervical disc herniation: PCN or PRF?