Clinical Trials Logo
  1. Home
  2. Intervertebral Disc Degeneration
  3. NCT04600544

Russian Disc Degeneration Study — RuDDS  

Genetic Predisposition to Disease Clinical Trial

Official title:
Disease-oriented Russian Disc Degeneration Study (RuDDS) Biobank Facilitating Functional Omics Studies of Lumbar Disc Degeneration

Clinical Trial Summary

The main aim of this study is to establish disease-oriented biobank to facilitate research in biology of the lumbar disc degeneration. Diverse biological samples (whole blood, plasma, disc tissue) along with MRI imaging, clinical, socio-demographic and various omics data (e.g. genomic and transcriptomic) will be available for researchers and clinicians for a variety of further multi-omics studies. It will lay the groundwork for the development of early diagnostics of DDD and its personalized treatment. The study is planned to enroll up to 1,100 patients with different grades of lumbar disc degeneration. It is planned to recruit patients within 36 months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04600544
Study type Observational [Patient Registry]
Source Novosibirsk State University
Contact Olga Leonova, PhD, MD
Phone +7 (383) 373-32-01
Email onleonova@gmail.com
Status Recruiting
Phase
Start date October 16, 2020
Completion date January 19, 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05020574 - Microbiome and Association With Implant Infections Phase 2
Recruiting NCT06057181 - Helix Research Network
Recruiting NCT04390269 - Immunogenetics Predictors With COVID-19
Recruiting NCT04427163 - Assesment of Multiomics Profiles in Health and Disease.
Completed NCT03597659 - PheWAS of a Polygenic Predictor of Thyroid Function
Recruiting NCT06399666 - Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation Recurrence Following Electrical Cardioversion
Active, not recruiting NCT04634032 - Gene Expression and DNA Variation Analysis of Sacs to Identify the Pathophysiology of Indirect Inguinal Hernia
Completed NCT04145817 - Breast Cancer Risk After Diagnostic Gene Sequencing N/A
Not yet recruiting NCT04788927 - Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Not yet recruiting NCT03234140 - Constitutional Genetics in Follicular Lymphoma N/A
Completed NCT01973075 - Genetic Etiology in Premature Ovarian Insufficiency N/A
Completed NCT00555503 - Registry of Mastectomy for Breast Cancer Risk Reduction N/A
Active, not recruiting NCT05524909 - Full-scale Intervention Study: Genetic Risk Communication and Wearables N/A
Suspended NCT04151368 - Surgical and Patient Reported Outcomes of Robotic Nipple-Sparing Mastectomy N/A
Completed NCT02422511 - Genomic Sequencing for Childhood Risk and Newborn Illness N/A
Completed NCT00677495 - Gluten-free Diet in Gluten-genetically Predisposed Subjects N/A
Recruiting NCT05759143 - Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing N/A
Enrolling by invitation NCT05721326 - Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition N/A
Active, not recruiting NCT05685810 - Genetic Determinants of Kidney Disease in People of African Ancestry With HIV
Recruiting NCT04903782 - Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer