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Influence of Leucine Enriched Amino Acids on Myofibrillar and Collagen Protein Synthesis

Interventional Clinical Trial

Official title:
Influence of Leucine Enriched Amino Acids on Myofibrillar and Collagen Protein Synthesis in Human Skeletal Muscle

Clinical Trial Summary

The primary objective will be to determine the effect of leucine-enriched essential amino acids (LEAA) compared to carbohydrate placebo on dietary incorporation of [D5] Phenylalanine & [D5] Glycine into the three skeletal muscle protein pools (myofibrillar, sarcoplasmic and collagen), both following resistance exercise and at rest, with the two tracers provided as a 'intrinsically labeled' bolus. Other outcomes will relate to molecular regulation of protein synthesis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05554653
Study type Interventional
Source University of Toronto
Contact
Status Active, not recruiting
Phase N/A
Start date October 1, 2022
Completion date August 2024
View Details
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