Rheumatoid Arthritis Clinical Trial
Official title:
Rituximab for the Treatment of Rheumatoid Arthritis-Associated Interstitial Pneumonia: A Pilot Study
This study will examine the course of patients with progressive rheumatoid arthritis
associated interstitial lung disease (RA-ILD) treated with rituximab for safety and
progression-free survival at 48 weeks. Safety of rituximab therapy in this disease will be
assessed through patient history, physical exams and laboratory parameters.
- Twelve male/or female patient with RA-associated lung disease (6 of each nonspecific
interstitial pneumonia (NSIP) and usual interstitial pneumonia (UIP) histological
subtype) will be enrolled
- The study involves 12 visits over 48 weeks
- Rituximab will be administered intravenously at Day 1 and Day 15 with repeat dosing at
six months.
n/a
Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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