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Autologous Lung Stem Cell Transplantation in Patients With Interstitial Lung Diseases

Interstitial Lung Diseases Clinical Trial

Official title:
Autologous Lung Stem Cell Transplantation in Patients With Interstitial Lung Diseases

Clinical Trial Summary

Interstitial lung diseases (ILD) are a group of diseases affecting the lung interstitium. The lung scarring that occurs in ILD is often irreversible with only mitigating therapy available so far. This study intends to carry out an open, single-armed, phase I/II clinical trial to investigate whether lung stem cells can regenerate damaged lung tissue. During the treatment, lung stem cells will be isolated from patients' own bronchi and expanded in vitro. After careful characterization, cultured cells will be injected directly into the lesion by fiberoptic bronchoscopy. The safety and efficacy of the treatment will be monitored by measuring the key clinical indicators.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02796781
Study type Interventional
Source Shanghai East Hospital
Contact
Status Completed
Phase Phase 1/Phase 2
Start date October 12, 2016
Completion date August 31, 2020
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