Immunosuppressant Combined With Pirfenidone in CTD-ILD

Status Active, not recruiting

Clinical Trial Summary

A prospective cohort study was used to observe the efficacy and safety of different immunosuppressive agents with/wo pirfenidone on CTD-ILD patients in Qilu Hospital of Shandong University for 36 months.The main research endpoints are lung function, patient dyspnea score, 6-minute walking distance, imaging indicators, primary disease activity, adverse reactions, etc.

Clinical Trial Description

This study will enroll 200 cases of connective tissue disease-related interstitial lung disease (CTD-ILD) patients in China, including inflammatory myopathy (IIM) patients, rheumatoid arthritis (RA) patients, systemic sclerosis (SSc) patients, Sjogren's syndrome (SS) patients and other connective tissue disease patients.According to the patient's condition,the participants plan to be treated with different immunosuppressive agents with/wo pirfenidone .Participants can choose to continue the study up to 36 months.The efficacy and safety of the treatment in CTD-ILD patients will be evaluated with lung function, quality of life / cardiopulmonary function assessment and other disease activity indices. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04928586
Study type	Interventional
Source	Qilu Hospital of Shandong University
Contact
Status	Active, not recruiting
Phase	Phase 4
Start date	August 16, 2019
Completion date	June 1, 2025

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