Identification Of Occupational Exposures In Patients With ILD

Interstitial Lung Disease Clinical Trial

— ILD  

Official title:

Identification of Occupational Exposures in Patients With Interstitial Lung Diseases (ILD)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04879082
• Other study ID #: A257
• Status: Completed
• Start date: May 15, 2020
• Est. completion date: April 15, 2021

Study information

• Verified date: March 2021
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Diffuse interstitial lung disease brings together a heterogeneous group of pulmonary pathologies, characterized by infiltrating and diffuse lesions of the pulmonary interstitium. The evolving risk of these ILD is pulmonary fibrosis, with the development of chronic respiratory failure. The process of the etiological diagnosis of ILD results from a multidisciplinary approach (pulmonologists, radiologists, occupational health specialists, anatomo-pathologists, etc…). Indeed, the multitude of possible causes of these diseases makes the etiological diagnosis difficult. Professional aetiologies are also frequently mentioned : pneumoconiosis, hypersensitivity pneumonitis, as a differential diagnosis. It therefore appears essential to deepen the professional aspect during the diagnostic process for ILD. Since May 2020, a professional interview has been systematically offered by the Occupational Pathology Consultation Center of the Hospital Center Lyon Sud, to patients followed by the team of Professor Vincent COTTIN, whose file was discussed in a multidisciplinary meeting. The data collected to constitute a database are the following variables: age, sex, diploma, professional course coded in CITP (International Standard Classification of Professions) and NAF (French Nomenclature of Activities), occupational exposures, smoking, risk factors non-professionals, clinical elements of ILD and elements relating to an occupational disease certificate. This database is anonymized.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150
• Est. completion date: April 15, 2021
• Est. primary completion date: March 15, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients with ILD.
• File discussed in a multidisciplinary meeting since May 2020 at the Louis Pradel Pneumological Hospital.
• Have benefited from a professional interview in the Occupational pathology consultation center of the Hospital Center Lyon Sud.

Exclusion Criteria:

• Patients with sarcoidosis.

Related Conditions & MeSH terms

• Interstitial Lung Disease
• Lung Diseases
• Lung Diseases, Interstitial
• Occupational Exposure

Intervention

Other:
• Professional course, occupational exposures
The data collected are the following variables: age, sex, diploma, professional course coded in CITP (International Standard Classification of Professions) and NAF (French Nomenclature of Activities), occupational exposures, smoking, risk factors non-professionals, clinical elements of ILD and elements relating to an occupational disease certificate. This database is anonymized. The precise diagnosis of ILD is retained during the multidisiciplinary meeting. Occupational exposures are assessed in specialized consultation : a first professional interview phase: The professional history is traced, listing the training courses followed and the trades carried out. The questioning is precise and focuses on the different tasks performed, and the products used. a second step, where a questionnaire is completed by the doctor: A list of specific substances is offered to the patient, who responds whether or not he thinks he has been exposed to them in his professional past.

Locations

Country	Name	City	State
France	Centre de consultation de pathologie professionnelle, Centre Hospitalier Lyon Sud	Pierre-Bénite

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Study the distribution of occupational exposures according to the types of ILD. The precise diagnosis is retained during the multidisiciplinary meeting.	Precise diagnosis of ILD : type of PID diagnosed	The precise diagnosis of ILD is retained immediately after the multidisiciplinary meeting.
Primary	Occupational exposures are assessed in specialized consultation by the occupational physician.	Occupational exposures	Occupational exposures are assessed immediately after the occupational consultation.