Cellular Scale Measures of Short-Term Retinal Atrophy Progression

Interstitial Cystitis, Chronic Clinical Trial

Official title:
Cellular Scale Characterization of the Retinal Pigment Epithelium-Photoreceptor Complex in Pentosan Polysulfate Sodium Toxicity

Status Recruiting

Clinical Trial Summary

Our goal is to determine the cellular scale changes that occur in subjects who have disease progression due to pentosan polysulfate sodium toxicity

Clinical Trial Description

The aim of this study is to determine the formation and progression of retinal changes caused by pentosan polysulfate sodium toxicity. To do this, we will measure how single cone photoreceptors respond to light in regions of the retina that are affected by pentosan polysulfate sodium toxicity. We will also measure how the retinal pigment epithelium, a layer of cells vital to photoreceptor health, change in shape and size over time. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05643157
Study type	Observational
Source	Indiana University
Contact	Kristen Bowles Johnson, O.D.,Ph.D.
Phone	812-855-8991
Email	kbowlesj@iu.edu
Status	Recruiting
Phase
Start date	November 1, 2022
Completion date	September 30, 2024

View Details

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