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Internal Disc Disruption clinical trials

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NCT ID: NCT04102761 Completed - Clinical trials for Internal Disc Disruption

The Use of PRP and BMC in Patients With Internal Disc Disruption Multicenter Prospective Randomized Controlled Trial in Patients With Internal Disc Disruption

Start date: March 27, 2018
Phase: N/A
Study type: Interventional

The condition being studied is chronic low back or leg pain in patients with internal disc disruption (IDD). The intervention to be studied is the intradiscal delivery of autologous Platelet Rich Plasma (PRP) or bone marrow concentrate (BMC) into the nucleus pulposus of the disrupted disc(s).

NCT ID: NCT01011816 Terminated - Back Pain Clinical Trials

Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® System

Start date: March 2010
Phase: Phase 3
Study type: Interventional

The purpose of this investigation is to establish the safety and efficacy of the Biostat System when used for treatment of chronic low back (lumbar) pain due to symptomatic internal disc disruptions (IDD) by comparing safety and efficacy outcome measures between one group receiving BIOSTAT BIOLOGX® Fibrin Sealant through the Biostat® Delivery Device and another group receiving a preservative-free normal saline control delivered with the Biostat Delivery Device.