Intermittent Fasting Clinical Trial
Official title:
Weekly ONe-Day WatER-only Fasting InterventionaL Trial for Low-Density Lipoprotein Cholesterol Reduction
The goal of this study is to determine how effective repeated fasting over 26 weeks (6
months) is at improving risk parameters that are surrogate endpoints for cardiovascular
diseases, metabolic dysregulation and cognitive impairments.
Subjects will be randomized 1:1 to water-only fasting or to their ad libitum usual diet, with
randomization performed within strata based on fasting history (≤180 hours or 181-720 hours
of total fasting for >12 consecutive hours per episode in the previous two years). Subjects
will be assessed at 4, 13 and 26 weeks following randomization.
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