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Clinical Trial Summary

Currently, recommendations for antibiotic testing (ATS) in adult intensive care have been published. The 2018 SFAR and the Abdul- Aziz et al expert conference recommend routine testing for β-lactams, aminoglycosides, linezolid, and vancomycin and provide plasma concentration goals. No recommendations have been made for the pediatric intensive care unit (PICU) population. However, several articles report suboptimal plasma concentrations for the most frequently used antibiotics in PICU. The University Hospital of Reunion is the reference center for the western region of the Indian Ocean. This region presents a large mixed population due to the migratory flow, as well as a specific bacterial ecology. This suggests that the data already collected on antibiotic dosage in other European studies may not be fully extrapolated to Reunion Island. It is in this context that we will study the plasma concentration of antibiotics for all children who received the most commonly used antibiotics (β-lactams, linezolid, vancomycin, and aminoglycosides) during their hospitalization in PICU.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05354635
Study type Observational
Source Centre Hospitalier Universitaire de la Réunion
Contact Lise PEIPOCH, MD
Phone +262 262 90 63 90
Email lise.peipoch@chu-reunion.fr
Status Not yet recruiting
Phase
Start date June 2022
Completion date June 2025

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