Mortality in Pediatric Intensive Care Unit

Intensive Care Units, Pediatric Clinical Trial

Official title:

Epidemiology of Death in the PICU of Southeast China

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02961153
• Other study ID #: fdpicu-01
• Status: Completed
• First received: October 26, 2016
• Last updated: April 9, 2018
• Start date: August 2016
• Est. completion date: April 2018

Study information

• Verified date: April 2018
• Source: Children's Hospital of Fudan University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

With the development of national economy and medical technology, patients can extend life rely on high-end medical facilities. At the same time, the continued treatment cannot bring benefits to children, even resulting in poor quality of life of children and bringing high medical costs. This makes the limited medical resources are unreasonable distributed. Research showed that PICU mortality rate halved over ten years ago, but the data did not include death cases who left hospital before death. However, the death number of out-hospital were more than death in-hospital. Therefore, the data cannot actually reflect China's mortality rate of PICU. The reason analysis was limited to the cause of the disease, and does not take the social, economic factors into account. This study include eight PICUs of children's Hospital PICU. Critically ill patients are prospectively studied from death risk factors, admission status, disease diagnosis, severity of illness, analyzing of the risk factors of death from disease diagnosis and death risk factors. In addition, we will illuminate the relationship of death and economic factor, especially for who died out-hospital after withdraw or stop treatment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 5000
• Est. completion date: April 2018
• Est. primary completion date: July 31, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 18 Years

Eligibility

Inclusion Criteria:

• ALL patients admitted to the PICU of eight study centers

Exclusion Criteria:

• Postoperative monitoring of patients with stable hemodynamics

• PCIS score >90 and not up to the United States PICU admission standards

Related Conditions & MeSH terms

• Intensive Care Units, Pediatric

Intervention

Other:
• death

Locations

Country	Name	City	State
China	Children'S Hosptial of Fuan University	Shanghai

Sponsors (1)

Lead Sponsor	Collaborator
Children's Hospital of Fudan University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pediatric Critical Illness Score(PCIS)		first 24 hours after admission
Primary	Pediatric Risk of Mortality score (PRISM III)		24 hours
Primary	Pediatric logistic organ dysfunction (PELOD) score		24hour
Secondary	all cause mortality		one year