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Pharmacokinetics-pharmacodynamics and Safety of Dexmedetomidine in Children

Intensive Care Unit Clinical Trial

Official title:
Pharmacokinetic-pharmacodynamic Analysis for Dosing Strategy and Evaluation of Safety and Efficacy of Dexmedetomidine in Children

Clinical Trial Summary

This study evaluates pharmacokinetics and pharmacodynamics of dexmedetomidine for children under sedation at intensive care unit after surgery. Patients will receive dexmedetomidine intravenously for 50 minutes after surgery as as sedation drug.

Clinical Trial Description

Dexmedetomidine, an alpha-2 adrenergic agonist, is being effectively used for procedural sedation or sedation at intensive care unit. However, the safety and efficacy profile are not yet established for children. Although there have been some studies regrading it, still there is no public guideline, therefore making it difficult to use dexmedetomidine in children. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04027829
Study type Interventional
Source Seoul National University Hospital
Contact
Status Completed
Phase Phase 2
Start date August 14, 2019
Completion date November 14, 2019
View Details
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