Intensive Care Unit Syndrome Clinical Trial
— MagiCCOfficial title:
Importance of Ionized Magnesium Measurement for Monitoring of Continuous Venovenous Haemodialysis With Citrate Anticoagulation
Verified date | May 2020 |
Source | University Hospital, Montpellier |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
It has been reported in several studies that ionized hypomagnesemia is associated with higher morbidity and mortality rates. During continuous renal replacement therapy with regional citrate anticoagulation (CRRT-RCA), the loss of magnesium has been reported to not be covered by magnesium concentration in ordinary dialysis fluid. This may lead to ionized hypomagnesemia. However the incidence of ionized hypomagnesemia in patients requiring CRRT-RCA remains unclear and need to be estimated to determine if ionized magnesium monitoring could be of interest. This study aim to assess the incidence of ionized hypomagnesemia induced by CRRT-RCA.
Status | Completed |
Enrollment | 40 |
Est. completion date | November 23, 2020 |
Est. primary completion date | October 1, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility | Inclusion criteria: - Consecutive patients admitted to the ICU and requiring continuous renal replacement therapy with regional citrate anticoagulation - age > 18 ans Exclusion criteria: - Persons under protection - Paritcipation rejections |
Country | Name | City | State |
---|---|---|---|
France | Uhmontpellier | Montpellier |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Montpellier | Novamedica Laboratories |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | assess the systemic ionized magnesemia change after 24h of CRRTsystemic variations of iMg | assess the systemic ionized magnesemia change after 24h of CRRT wiith regional citrate anticoagulation | Day 0 and Day 1 | |
Secondary | Proportion of patients with heart rhythm disturbances | Proportion of patients with heart rhythm disturbances | 1 day | |
Secondary | Assessment of morbidity and mortality | Assessment of morbidity and mortality | 1 day |
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