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Gut Microbiome and ICU Delirium Post Cardiac Surgeries

Intensive Care Unit Delirium Clinical Trial

Official title:
Gut Microbiome and Gut Barrier Function in ICU Delirium Post Cardiac Surgery

Clinical Trial Summary

ICU delirium are assessed by clinical nurses twice every day. Delirious patients are matched with patients according to their disease, gender and age range(±3 years). Stool samples for gene sequencing are collected. Gut barrier function are studied with several serum biomarkers (endotoxin, etc.). Ecological analyses, regression models and mediation equation will be performed.

Clinical Trial Description

ICU delirium are assessed by clinical nurses twice every day using Confusion Assessment Method for the ICU (CAM-ICU). Delirious patients are matched with patients according to their disease, gender and age range(±3 years). Stool samples for gene sequencing are collected within 24 hours after surgeries. Gut barrier function are studied with several serum biomarkers (endotoxin, etc.). Ecological analyses, regression models and mediation equation will be performed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04056338
Study type Observational
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact
Status Completed
Phase
Start date January 1, 2019
Completion date December 30, 2019
View Details
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