Satiety Clinical Trial
Official title:
Incorporating Avocados in Meals: Effect on Glycemic Index, Insulin Response, Satiety and Satiety-related Gastrointestinal Peptides in Humans
The purpose of this study is to examine the effect of incorporating avocados in meals on
post-ingestion glycemic index, insulin response, sensations of satiety and on
appetite-related gastrointestinal peptide and hormone release. Also the effect of consuming
avocado containing meals on the caloric intake of participants in subsequent eating episodes
will be explored.
Each subject will participate in one intervention for one day, wait one or two weeks, come
for another intervention, wait one or two weeks and come for a final intervention- three in
total. Participants will be randomly assigned to one of six treatment sequences.
Postprandial response to the control and two avocado-containing test meals will be assessed
and compared using a 3 x 3 single blind cross-over design. The Subjects will be between 25
and 60 years old, female or male, with a BMI of 23 to 32, stable weight, no sports
involvement, non-smoking and not dependent on caffeine. Thirty subjects will be recruited.
n/a
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator)
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