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Insulin clinical trials

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NCT ID: NCT06178874 Not yet recruiting - Critical Illness Clinical Trials

Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness Hyperglycemia

Start date: December 2023
Phase: N/A
Study type: Interventional

The role of ultralong insulin in the control of the blood glucose level in diabetic patients is well known, the current study will discuss the role of ultralong insulin in controlling of hyperglycaemia in critical illness defined as failure or impending failure of an organ

NCT ID: NCT06021275 Recruiting - Scars Clinical Trials

Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.

NCT ID: NCT05958368 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes

AVOCADO-T2D
Start date: October 10, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to assess the effects of Hass Avocados on glycemic control. The investigators hypothesize that Hass Avocado consumption will reduce fasting blood sugar compared to an isocaloric amount of other fruit during controlled feeding.

NCT ID: NCT05692739 Recruiting - Dry Eye Clinical Trials

Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye

Start date: October 5, 2022
Phase: Phase 4
Study type: Interventional

This is a parallel randomized controlled trial for the treatment of dry eye disease. The main objective is to investigate the efficacy and safety of the use of insulin eye drops in the control of moderate-severe dry eye disease. Topical insulin drops will be compared to the current gold standard treatment, cyclosporin and placebo (artificial tears).

NCT ID: NCT05464966 Completed - Insulin Clinical Trials

The Primary Objective of This Study Was to Investigate the Effect of Insulin on Myocardial Perfusion and Cardiac Function in Patients Undergoing Cardiac Surgery for CPB Using Transesophageal Echocardiography (TEE) to Detect CSBF

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The primary objective of this clinical trial was to investigate the effects of insulin on myocardial blood flow reflected by CSBF which was evaluated by TEE. The second aim was to observe the effect of insulin on cardiac function and markers of myocardial damage.

NCT ID: NCT05448378 Completed - Insulin Clinical Trials

Evaluation of D-chiro-inositol Treatments

Start date: June 4, 2022
Phase: N/A
Study type: Interventional

Healthy women will take tablets containing 600 mg D-chiro-inositol twice per day for one month. We will evaluate metabolic and hormonal.parameters, as insulienmia, glycemia, estradiol, testosterone.

NCT ID: NCT05171400 Recruiting - Wound Healing Clinical Trials

A New Drug Delivery System - Silk Fibroin Film Loaded or Not With Insulin on Palatal Mucosa Wound Healing

Start date: July 2, 2021
Phase: N/A
Study type: Interventional

The aim of the present study is to evaluate using clinical, patient-centered, immunological, microbiological, and histological parameters, the effect of silk fibroin films loaded or not with insulin in the repair of palatal mucosa open wounds.

NCT ID: NCT04833413 Recruiting - Insulin Clinical Trials

Regimen Switch After Intensive Insulin Therapy

Start date: April 15, 2021
Phase:
Study type: Observational

Insulin intensive therapy have traditionally been considered a sequential therapy in type 2 diabetes last choice, a number of guidelines and consensus recommendations insulin intensive therapy can be as obvious hyperglycemia in patients with newly diagnosed T2DM part of a line, a subset of patients after insulin intensive treatment target often need to change to other treatments, especially for senile diabetes patients, due to its self management ability, simplify the insulin solution is more urgent. Current clinical guidelines do not provide specific clinical guidance, such as the timing and method of switch after initial insulin intensive therapy. The purpose of this study was to explore the timing, suitable population and conversion methods of insulin regimens after treatment.

NCT ID: NCT04739371 Completed - Insulin Clinical Trials

Food Intake and Intra-Nasal Insulin for African American Adults (FIINAAL)

FIINAAL
Start date: June 17, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to investigate brain insulin's relationship with food intake in African Americans. Facilitating insulin's entrance into the brain through a nasal spray is currently being studied as a way to prevent or treat Alzheimer's disease. However, brain insulin may also have an impact on food intake. This study is designed to help researchers understand how different factors related to Alzheimer's disease (i.e. APOE genotype and cognitive functioning) influence brain insulin's relationship with food intake.

NCT ID: NCT04711382 Completed - Type 1 Diabetes Clinical Trials

The Use of Faster Acting Aspart in Type 1 Diabetes Patients

Start date: January 29, 2018
Phase:
Study type: Observational

Data on switching from traditional mealtime insulins to fast-acting insulin aspart (Fiasp) in routine clinical practice are sparse. The aim was to evaluate the efficacy and safety of switching from traditional mealtime insulin to Fiasp in a "real-world" clinical practice setting in people with type 1 diabetes in Belgium.