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NCT ID: NCT04710186 Recruiting - Clinical trials for Androgen Receptor Abnormal

AR, IGF-IR, IR and Peripheral Artery Disease

ANIMALPAD
Start date: August 1, 2018
Phase:
Study type: Observational

Peripheral artery Disease (PAD) is a major cardiovascular disease that can impair quality of life (QoL). It affects more often male patients and its pathophysiology is not completely known. Probably androgen receptors and metabolism alteration may play an important role in the onset and in the progression of PAD towards its dreadful complications. The aim of this study is to evaluate the role of Androgen Recetpr , IGF-I receptor, and Insulin Receptor on the arterial wall of male patients with PAD undergoing open revascularization surgery.