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Effects of Suvorexant in Patients With Chronic Obstructive Pulmonary Disease (MK-4305-032)

Insomnia Clinical Trial

Official title:
A Study to Evaluate the Effects of MK-4305 in Patients With Chronic Obstructive Pulmonary Disease

Clinical Trial Summary

This study will evaluate the safety, tolerability, and effect of multiple doses of suvorexant (MK-4305) on respiratory function in participants with chronic obstructive pulmonary disease (COPD). This is a crossover study, so all participants will receive both suvorexant and placebo while on study. The primary hypothesis of this study is that multiple doses of suvorexant do not produce a clinically significant reduction of mean oxygen saturation (SaO2) during total sleep time in participants with COPD, as compared to placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01293006
Study type Interventional
Source Merck Sharp & Dohme Corp.
Contact
Status Completed
Phase Phase 1
Start date March 25, 2011
Completion date February 22, 2012
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