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Insomnia Disorder clinical trials

View clinical trials related to Insomnia Disorder.

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NCT ID: NCT03545191 Completed - Insomnia Disorder Clinical Trials

Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder

Start date: June 4, 2018
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to assess efficacy and safety of ACT-541468 (daridorexant) in adult and elderly subjects with insomnia disorder. Efficacy will be evaluated on objective and subjective sleep parameters.

NCT ID: NCT03328585 Completed - Insomnia Disorder Clinical Trials

Telemedicine vs. In-person Delivery of Cognitive Behavioral Treatment of Insomnia: a Mixed Methods Analysis

Start date: November 21, 2017
Phase: N/A
Study type: Interventional

Cognitive behavioral therapy for insomnia (CBT-I) has been the 'gold standard' for the treatment of insomnia. There is a need to increase access to treatment, particularly for patients in more rural locations where providers may be scarce. One solution is to utilize telemedicine which is "the use of electronic communications to provide and support health care when distance separates the provider from the patient." So the purpose of the study is to determine if receiving CBT-I by video teleconferencing works just as well as in-person treatment.

NCT ID: NCT03056053 Completed - Insomnia Disorder Clinical Trials

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

Start date: February 15, 2017
Phase: Phase 2
Study type: Interventional

The main study objective is to assess the content validity and the psychometric characteristics of the Insomnia Daytime Symptoms and Impacts Questionnaire™ (IDSIQ™).

NCT ID: NCT02952820 Completed - Insomnia Disorder Clinical Trials

Long-term Study of Lemborexant in Insomnia Disorder (SUNRISE 2)

Start date: November 15, 2016
Phase: Phase 3
Study type: Interventional

The key objectives of this study are to determine, using sleep diaries, whether lemborexant at the doses 5 milligrams (mg) and 10 mg is superior to placebo on subjective sleep onset, subjective sleep efficiency, and subjective sleep maintenance in participants with insomnia disorder.

NCT ID: NCT02841709 Completed - Insomnia Disorder Clinical Trials

Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia Disorder

Start date: November 28, 2016
Phase: Phase 2
Study type: Interventional

This study evaluates the dose response of ACT-541468 on the change of wake after sleep onset (WASO) assessed by polysomnography (PSG) on the first 2 days of each treatment period.

NCT ID: NCT02839200 Completed - Insomnia Disorder Clinical Trials

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

Start date: October 4, 2016
Phase: Phase 2
Study type: Interventional

This study evaluates the dose response of ACT-541468 on the change of WASO from baseline to Days 1 and 2, assessed by PSG.

NCT ID: NCT02629913 Completed - Insomnia Disorder Clinical Trials

Is Internet-based Self-help Effective for the Treatment of Insomnia Disorder?

Start date: January 2016
Phase: N/A
Study type: Interventional

The Swiss company mementor has recently developed an interactive self-help intervention for the treatment of insomnia entitled mementor somnium. This programme is based on the guidelines for cognitive-behavioural therapy. mementor somnium consists of 6 online sessions. An animated personal sleep coach provides relevant audio-information and asks questions to which the patient is invited to respond. The components of the programme flexibly adapt to the patient's responses. Aside from psycho-education, exercises and an instruction for sleep restriction, mementor somnium includes a cognitive restructuring intervention in terms of a Socratic dialogue. This Socratic dialogue, implemented by the animated sleep coach, is based on a complex algorithm in the shape of an decision tree. University of Zurich's Department of Psychology in Switzerland will test the effectiveness of mementor somnium in a randomised controlled trial with three assessment times (pre, 6-weeks post and 3-months follow-up). Patients suffering from insomnia will be allocated randomly to either the active intervention group or the waitlist control group. Participants will have access to the programme mementor somnium for six weeks. Primary outcome measure is the Insomnia Severity Index, secondary outcome measures are Beck Depressions-Inventory revised (BDI-II), Brief Symptom Inventory 18, and the SF-12 Health Survey. Additionally, sleep diary data will be collected.

NCT ID: NCT02571452 Completed - Insomnia Disorder Clinical Trials

Brief Behavioral Insomnia Treatment Study

BBTI
Start date: January 6, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a brief, behavioral treatment for insomnia is effective in addressing social and occupational functioning and overall health among Veterans with insomnia disorder.

NCT ID: NCT02409264 Completed - Insomnia Disorder Clinical Trials

The Effect of Individualised Homeopathic Treatment of Insomnia Disorder in Females

Start date: January 2015
Phase: Phase 2
Study type: Interventional

In South Africa, 27% of adult males and 31% of adult females experience insomnia. Insomnia may lead to feelings of fatigue and sleepiness, mood disturbances, cognitive difficulties, and may exacerbate symptomatology of co-morbid diseases. Current conventional treatment for insomnia includes both psychological and drug therapies. These conventional medications potentially may lead to dependency and withdrawal symptoms. Individualised homeopathic treatment is a process in which a homeopath selects the most appropriate remedy for the treatment of a condition in accordance with the fundamental principles of homeopathy. This treatment protocol may offer safe and effective treatment for insomnia disorder, however, more research is required on the subject. The aim of this study is to determine the effect of individualised homeopathic treatment of insomnia disorder in females using detailed case studies and the Insomnia Severity Index.

NCT ID: NCT02350309 Completed - Insomnia Disorder Clinical Trials

Study to Evaluate the Effect of 2 Dosage Strengths of Lemborexant (E2006) on a Multiple Sleep Latency Test in Participants With Insomnia Disorder

Start date: December 13, 2014
Phase: Phase 1
Study type: Interventional

This is a single-dose, randomized, placebo-controlled, 3-way crossover study of 2 dosage strengths of lemborexant (5 mg and 10 mg) in participants with insomnia disorder.