Inoperable Gastric Cancer Clinical Trial
Patients diagnosis with inoperable gastric cancers are treated with palliative chemotherapy.
Palliative chemotherapy had proven to be better overall survivals and quality of life in
unresectable advanced gastric cancer. NCCN guideline suggested two or three drug cytotoxic
regimen as a first line therapy. But response rate of those regimens is about 50 percent.
Disappointingly most of cases are about to experience progression of disease.
Second line regimens of palliative chemotherapy are also have shown its efficacy and
recommended within patients with better performance status. But There is still lack of
evidences in gastric cancer patients second line chemotherapy. Several phase II trial those
subjects are 2nd line palliative chemotherapy in gastric cancer had suggested that
irinotecan, taxane, oxaliplatin, oral fluorouracil.Investigator assessed whether cisplatin
in combination with paclitaxel would increase response rate in patient previously treated
for advanced gastric cancer compared with FOFIRI regimen.
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