the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block

Injury of Upper Limb Clinical Trial

Official title:

the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02961361
• Other study ID #: Dex
• Status: Completed
• Phase: Phase 4
• Start date: November 12, 2016
• Est. completion date: May 25, 2017

Study information

• Verified date: February 2023
• Source: The First Hospital of Qinhuangdao
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Dexmedetomidine is an α-2 adrenoreceptor agonist and has been extensively used through intravenous infusion，in order to improved the quality of block in regional anesthesia. In this prospective, randomized study, the authors focus on the effect of dexmedetomidine mixed with ropivacaine in coracoid approach brachial plexus block.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 25, 2017
• Est. primary completion date: March 30, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

1. American Society of Anesthesiologists (ASA) physical status I or II;

2. Aged 18-60 years;

3. The elbow, forearm, wrist or hand surgery

Exclusion Criteria:

1. History of allergy to local anesthetics;

2. Coagulation dysfunction, neuromuscular disease or local infection;

3. The operation time is longer than the local anesthetics effective time.

Related Conditions & MeSH terms

• Arm Injuries
• Injury of Upper Limb

Intervention

Drug:
• ropivacaine
40 ml 0.375% ropivacaine was injected after Locating brachial plexus.
• ropivacaine mixed with dexmedetomidine
40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The First Hospital of Qinhuangdao

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	duration time	effective analgesia time	once per hour after surgery until 24 hours after surgery
Secondary	onset time		5,10,15,20,25,30 min after injection
Secondary	Visual analogue scale		2,6,12,24hour after injection