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Injection Site Irritation clinical trials

View clinical trials related to Injection Site Irritation.

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NCT ID: NCT05225610 Completed - Clinical trials for Injection Site Irritation

Valsalva Manoeuvre and Intravenous Dexmedetomidine on Attenuating Pain During Propofol Injection in Upper GIT Endoscopy

Valsalva
Start date: February 19, 2022
Phase: N/A
Study type: Interventional

No previous study has cited the use of the Valsalva manoeuvre for the reduction of pain on propofol injection in comparison with dexmedetomidine injection. Therefore, investigators plan a study to evaluate the analgesic efficacy of the Valsalva manoeuvre in alleviating pain during propofol injection as compared to dexmedetomidine injection.

NCT ID: NCT04673500 Completed - Clinical trials for Injection Site Irritation

Assessment of Pain on Propofol Injection.

Start date: May 2013
Phase: N/A
Study type: Interventional

Title: Assessment of pain on lidocaine-Propofol admixture injection: Comparing large antecubital vein and small vein dorsum of hand. - Objective: To evaluate the pain on Propofol - lidocaine admixture injection using different sizes of veins on upper limb. - Design: Prospective randomized clinical trial Place and duration of study: Department of Anesthesia, King Saud University Riyadh May 1, 2013 - May 31, 2014). - Patient and methods: Total 160 adult patients were divided in two groups. Age 20-50 years of either gender, American Society of Anesthesiologist (ASA) class 1 and 2, scheduled for elective surgery under general anesthesia were included in the study. Patients with known history of allergy to lidocaine or Propofol, obese patients, anticipated difficult intubation, already on any analgesics and pregnant patients were excluded from the study. Both groups received an admixture of Propofol (1%) - lidocaine (2%) on induction of anesthesia through antecubital vein (Group- 1) or through a vein on dorsum of hand (Group- 2). Pain was assessed as none, mild, moderate or severe. Results: Moderate to severe pain on intravenous injection of Propofol-lidocaine admixture through antecubital vein and small vein on dorsum of hand was 20% vs 71%. Conclusion: There is marked reduction of pain when Propofol - lidocaine admixture was injected through antecubital vein as compared to small vein on dorsum of hand. - Key words: Propofol, injection, pain

NCT ID: NCT04582032 Completed - Clinical trials for Injection Site Irritation

Effects of Cyclooxygenase (COX) 1-2 Inhibitors on Prevention of Rocuronium Injection Pain

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Purpose : The aim of the study is to investigate the effects of cox inhibitors as a rescue agent against the rocuronium pain Methodology : Sixty patients enrolled for the general anesthesia enrolled in this study. Patients were allocated into two groups (Group 1: Dexketoprofen group, Group 2: Control group) .Pain was evaluated by during rocuronium injection, patients were scored by a scale showed below. 0;No movement response to injection 1. Mild movement response to injection 2. Hand withdrawal response to injection 3. Arm withdrawal response to injection Investigators also evaluated the pain with 2 questions when the patient was in the recovery room. Question 1.What was the last feeling before participants fall into sleep? question 2. Did participants feel any pain on participants's hand during medication injection for anesthesia?

NCT ID: NCT04555980 Completed - Pain Syndrome Clinical Trials

Warm Patch Decrease Propofol Injection Pain

Start date: March 20, 2020
Phase: N/A
Study type: Interventional

Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection. Using an air warmer to warm the arm can also reduce the pain caused by propofol injection. Investors suspect that treatment with a warming patch (covering the injection site) can also reduce the pain caused by propofol injection.

NCT ID: NCT04436666 Completed - Clinical trials for Injection Site Irritation

Virtual Reality, Ice Application and Self-injection and Self-test Fair, Pain and State Anxiety

Start date: July 15, 2020
Phase: N/A
Study type: Interventional

AİM:The aim of this study is to control the fears and anxieties of Type 2 diabetics in insulin injection and blood glucose measurement with motivational videos and Ice applications to be applied with virtual reality glasses. Material and Methods: The research is designed as a semi-experimental model with pretest-posttest control groups. The research will be carried out in the endocrine services located in Turgut Özal Medical Center in Malatya province. The universe of the research will be 2113 Type 2 diabetes patients who are being treated in the hospital specified on the specified dates, who are injecting insulin and following blood sugar. According to the analysis of the power, the sample of the research is composed of an experiment effect of 0.5% with bilateral significance level, 95% confidence interval determined with 5% error level, the experiment group to be applied with 80% Reality with 80% representation power, and the control group with 80 ice application. will create a total of 240 Type 2 diabetes patients.In the collection of the data, the Participant Presentation Form developed by the researcher, Diabetes Fear of Self Injecting and Self-testing Questionnaire-D-FISQ, State Anxiety Scale and VAS will be used.

NCT ID: NCT02524743 Completed - Clinical trials for Injection Site Irritation

The Prevention of Pain Associated With Rocuronium Injection

Start date: May 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether efficacy of different doses of lidocain and acetaminophen for the prevention of rocuronium injection pain and frequency of withdrawal movements during the general anesthesia induction period.

NCT ID: NCT01824758 Completed - Clinical trials for Injection Site Irritation

Effect of Esmolol on Pain Due to Rocuronium

Start date: March 2013
Phase: Phase 4
Study type: Interventional

90 American society of anesthesiology (ASA) physical status I and II patients undergoing general anesthesia for elective surgery will be included in the study. Patients will be randomized into three groups. Group E will receive esmolol (1 mg/kg), Group IL lidocaine (0.5 mg/kg)and Group C placebo(NaCl 0.9%, 5 mL), followed by a 0.05 mg/kg rocuronium. After intravenous induction with propofol, adequate muscle relaxation for intubation will be received by 0.5 mg/kg rocuronium.