Inguinal Hernia Clinical Trial
Official title:
Observational Cross-sectional Study on the Association Between Inguinal Hernias and Arterial Diseases
Inguinal hernias are associated with problems related to the venous system by the linking to extracellular matrix alterations (ECM). On the other hand, arterial diseases (arterial aneurysms, carotid, stenosis, peripheral artery disease) are widespread in the general population and may share others pathological pathways related to ECM impairment. Aim to this study is to evaluate the prevalence of arterial diseases in patients with inguinal hernia.
Previous studies showed the correlation between inguinal hernias and venous disease. The
common pathophysiological pathway between these clinical conditions is linked to
extracellular matrix (ECM) alterations. Arterial diseases, mainly represented by carotid
stenosis, peripheral artery disease and arterial aneurysms, are widespread in western
population and are responsible of high rates of morbidity and mortality. These diseases are
also related to some ECM alterations.
Aim of this cross-sectional study is to evaluate the prevalence of arterial disease among
patients with inguinal hernias. The primary endpoint of this study is to provide new
epidemiological evidences on this association that may help physicians in novel preventive
strategies. The study will consider the inclusion of consecutive patients assessed for
inguinal hernia over 1 year period in order to study the prevalence of concomitant arterial
disease, by means of office visit, echo duplex scan of the aorta and its main branches,
carotid arteries and lower limb arteries.
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