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Inguinal Hernia clinical trials

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NCT ID: NCT03438786 Not yet recruiting - Inguinal Hernia Clinical Trials

Trans-inguinal Pre-peritoneal Hernioplasty Versus Lichtnestein's Technique in Inguinal Hernia Repair

TIPP
Start date: March 2018
Phase: N/A
Study type: Interventional

Mesh repair of inguinal hernia is the most common operation performed on general surgical patients. Approximately 20 million groin hernioplasties are performed each year worldwide. Countless studies have been reported in the medical literature in attempts to improve the overall outcomes following hernia operations and, due to this fact, the procedure has evolved immensely, especially over the last few decades. Recurrence of inguinal hernia was initially a significant problem. Lichtenstein repair (LR), recurrence rate has consistently been reported as low as 1-4%[2], a drop from up to 10%. But increased incidence of chronic groin pain following LR. Transinguinal preperitoneal (TIPP) inguinal hernia repair with soft mesh has been reported as a safe anterior approach with a preperitoneal mesh position . Theoretically, TIPP repair may be associated with lesser chronic postoperative pain than Lichtenstein's technique due to the placement of mesh in the preperitoneal space to avoid direct regional nerves dissection and their exposure to bio-reactive synthetic mesh. The placement of mesh in this plane without using any suture for fixation and lack of mesh exposure to regional nerves was assumed to result in the reduced risk of developing chronic groin pain. So aim of our study to prove less hospital stay and complication and cost effectiveness for preperitoneal meshplasty

NCT ID: NCT03314259 Not yet recruiting - Inguinal Hernia Clinical Trials

Prophylactic Alpha-blockers in the Prevention of Urinary Retention Post Inguinal Hernia Repair

Start date: December 1, 2017
Phase: Early Phase 1
Study type: Interventional

Post operative urinary retention ( POUR) is caused by sympathetic activation of the internal urethral sphincter after surgery. The smooth muscles of the around the internal urethral sphincter have been demonstrated to be rich in alpha-1 adrenergic receptors. Our research idea is novel because there has been no prior prospective study conducted using alpha-blockers to reduce post-operative urinary retention in patients undergoing inguinal hernia repair. The proposed research is important as existing studies that sought to understand POUR have merely established the risks factors involved. Despite so, the incidence of POUR remains high and no studies to date have investigated the use of specific interventions to reduce the risk of POUR. This is essential as patients who develop POUR have also been successfully shown to have significantly longer length of hospitalisation. Besides, the development of POUR can also cause significant pain/discomfort, increase risks of long-term urethral catheterisation and predispose patients to urinary tract infections

NCT ID: NCT03128216 Not yet recruiting - Inguinal Hernia Clinical Trials

Local Anesthetic Infiltration VS Trasversalis Fascia Block VS Spinal Anesthesia

Start date: April 2017
Phase: N/A
Study type: Interventional

Propose to comparison effectiveness of blind local anesthetic infiltration with ultrasound guided Transversals Fascia Block and Spinal Anesthesia in patients undergoing to inguinal hernia repair surgery. The effectiveness is defined as pain control during intraoperative and time need to reach hospital discharge criteria in the post-operative period.

NCT ID: NCT02932033 Not yet recruiting - Inguinal Hernia Clinical Trials

Trial Comparing Tack Versus Histoacryl Mesh Fixation After Endoscopic TEP(Total Extraperitoneal) Repair for Bilateral Inguinal Hernia

TEP
Start date: November 2016
Phase: N/A
Study type: Interventional

This prospective randomized trial is performed to analyze the post-operative pain (acute and chronic) after endoscopic TEP repair after bilateral inguinal hernia repair.

NCT ID: NCT02928146 Not yet recruiting - Inguinal Hernia Clinical Trials

Lichtenstein Versus TAPP and TEP in Groin Hernioplasty

TAPP&TEP
Start date: January 2017
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effectiveness of various methods of inguinal hernia repair and to evaluate techniques of synthetic mesh fixation during laparoscopic and open hernia repair.

NCT ID: NCT02788812 Not yet recruiting - Inguinal Hernia Clinical Trials

QOL in Incarcerated Inguinal Hernias: TAPP Vs Open Repair

Start date: June 2016
Phase: N/A
Study type: Interventional

To determine if there is a difference in the quality of life in between patients who undergoes laparoscopic transabdominal pre-peritoneal (TAPP) or modified Lichtenstein hernioplasty

NCT ID: NCT02723045 Not yet recruiting - Inguinal Hernia Clinical Trials

Quality of Life of TEP vs Lichtenstein Hernioplasty

Start date: April 2016
Phase: N/A
Study type: Interventional

To determine if there is a difference in the quality of life in between patients who undergoes laparoscopic totally extra-peritoneal (TEP) or modified Lichtenstein hernioplasty

NCT ID: NCT02646722 Not yet recruiting - Inguinal Hernia Clinical Trials

Relation Between Withdrawal Movement for Rocuronium and Emergence Agitation

Start date: January 2016
Phase: N/A
Study type: Observational

Rocuronium results in burning pain on injection site. It can be reduced by local anesthetics or opioid, but still some patients, especially in children, show withdrawal movement for pain. This might resulted from individual pain sensitivity. Emergence agitation (EA) in children is quite frequent postoperatively and is known to be associated with postoperative pain. If a patient is susceptible to postoperative pain, he or she would have high probability of EA postoperatively. Therefore, the investigators explore the relation of withdrawal movement of rocuronium and EA.

NCT ID: NCT02646709 Not yet recruiting - Inguinal Hernia Clinical Trials

The Effect of Different Dose of Ketamine With Low Dose Rocuronium in Children

Start date: January 2016
Phase: Phase 4
Study type: Interventional

Rocuronium is suitable for rapid induction within 60-90 seconds and its effect last 24-40 minute after single bolus injection. For outpatient surgery with short operation time, low dose rocuronium is frequently used for rapid recovery at the expense of compromised intubating condition. For better intubating condition, ketamine can be used. However, appropriate dose of ketamine with low dose rocuronium is not established yet. This study, 3 different doses of ketamine with low dose rocuronium will be compared for appropriate intubating condition.

NCT ID: NCT02634255 Not yet recruiting - Inguinal Hernia Clinical Trials

The Onset Time of Rocuronium in Emergency and Elective Surgery

Start date: December 2015
Phase: Phase 3
Study type: Interventional

Rocuronium, a nondepolarizing neuromuscular blocking agent, is used in general anesthesia to provide conditions for endotracheal intubating. Recommended dose is 0,6 mg/kg and 90 seconds after intravenous injection, patients can be intubated. Anxiety levels may vary in patients undergoing emergency and elective surgery. Patients undergoing emergency surgery may display exaggerated laryngoscopic responses. The purpose of this study is to investigate the effect of patient anxiety levels on the onset time of rocuronium in terms of anxiety scores and train of four (TOF) 0.1 times.