Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails

Ingrown Nail Clinical Trial

Official title: Topical Collagen-Silver Versus Standard Care Following Phenol Ablation of Ingrown Nails: A Randomized Controlled Trial

Status Recruiting

Clinical Trial Summary

This study's purpose is to prospectively determine whether topical therapy with an oxidized regenerated cellulose collagen-silver compound is more effective than the current standard of topical antibiotic therapy for care following the removal of an ingrown toenail. Eighty adult patients with ingrown toenails will be recruited. Each patient will randomly be assigned to apply either topical silver sulfadiazine cream (standard antibiotic) or the novel collagen-silver compound to their nail bed daily, following removal of the ingrown portion of nail. Patients will return for follow up visits weekly, until healing has occurred or twelve weeks have passed. Healing will be defined as resolution of drainage and inflammatory changes surrounding the nail border.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Ingrown Nail
• Nails, Ingrown

• NCT number: NCT00641433
• Study type: Interventional
• Source: Rosalind Franklin University of Medicine and Science
• Contact: David G Armstrong, DPM, PhD
• Phone: 847-578-8440
• Email: david.armstrong@rosalindfranklin.edu
• Status: Recruiting
• Phase: N/A
• Start date: November 2005
• Completion date: May 2008