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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05192733
Other study ID # Req-2021-01236
Secondary ID
Status Completed
Phase
First received
Last updated
Start date November 4, 2021
Est. completion date February 15, 2022

Study information

Verified date March 2022
Source Centre Hospitalier Universitaire Vaudois
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The PRICE study primarily aims to identify predictors of early extubation following elective infratentorial craniotomy in adults. It also aims to (i) measure the rate of early extubation in different clinical settings; and (ii) study how the decision to extubate early is made and communicated in clinical practice. The first phase of the study (PRICE1) is a brief online survey addressed to physicians in charge of neurosurgical patients (neuroanesthesiologists, neurosurgeons, neurocritical care specialists) in multiple countries.


Recruitment information / eligibility

Status Completed
Enrollment 190
Est. completion date February 15, 2022
Est. primary completion date February 15, 2022
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Physician actively involved in delivering care to neurosurgical patients - Physician formerly involved in delivering care to neurosurgical patients Exclusion Criteria: - Has already completed the survey

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Survey
This is a cross-sectional practice survey. There is no intervention.

Locations

Country Name City State
Switzerland Centre Hospitalier Universitaire Vaudois Lausanne Vaud

Sponsors (6)

Lead Sponsor Collaborator
Centre Hospitalier Universitaire Vaudois Camille Levy, Hervé Quintard, Lien Jakus, Nicolai Goettel, Torstein Meling

Country where clinical trial is conducted

Switzerland, 

References & Publications (2)

Cai YH, Wang HT, Zhou JX. Perioperative Predictors of Extubation Failure and the Effect on Clinical Outcome After Infratentorial Craniotomy. Med Sci Monit. 2016 Jul 12;22:2431-8. — View Citation

Cata JP, Saager L, Kurz A, Avitsian R. Successful extubation in the operating room after infratentorial craniotomy: the Cleveland Clinic experience. J Neurosurg Anesthesiol. 2011 Jan;23(1):25-9. doi: 10.1097/ANA.0b013e3181eee548. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Prevalence of early extubation Percentage of patients being extubated early, as estimated by responders. Early extubation is defined as extubation at the end of surgery, in the operating room, prior to discharge to recovery or intensive care. 3 months
Secondary Inventory of perceived main predictors of early extubation Participants to the survey can select up to 3 of the following options:
Survey options are:
Patient's level of consciousness Evidence of brainstem dysfunction Patient's physical status prior to surgery History or suspicion of difficult airway Preoperative imaging Duration of surgery Course of surgery Time of day when surgery ends Other (to be completed by responder)
3 months
Secondary Personnel perceived to make the decision to extubate early Participants to the survey can select 1 or several of the following options:
Anesthesiologist Neurosurgeon Neurocritical care physician
3 months
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