Invasive Pulmonary Aspergillosis Complicating Influenza Infection

Influenza With Pneumonia Clinical Trial

Official title: Invasive Pulmonary Aspergillosis Complicating Influenza Infection in Critically Ill Patients: a Prospective, Observational, Multicenter Case Control Registration Study

Status Completed

Clinical Trial Summary

Study the incidence and outcome of invasive pulmonary aspergillosis (IPA) in ICU patients with severe influenza and in influenza-negative control patients with severe community-acquired pneumonia

Clinical Trial Description

This prospective multicentre case-control registration study in Dutch and Belgian ICUs will assess the difference in incidence and outcome of invasive pulmonary aspergillosis (IPA) in ICU patients with severe influenza compared with influenza-negative control patients with severe community-acquired pneumonia during the coming three influenza seasons (2017-2020). The study will further assess the differences in clinical characteristics and risk factors between influenza patients with and without invasive aspergillosis. All consecutive patients aged 18 or older admitted to ICU during the inclusion period with respiratory distress due to influenza positive/negative community acquired pneumonia (CAP) will be included. ;

Related Conditions & MeSH terms

• Aspergillosis
• Aspergillosis Invasive
• Influenza With Pneumonia
• Influenza, Human
• Invasive Pulmonary Aspergillosis
• Pulmonary Aspergillosis

• NCT number: NCT03391492
• Study type: Observational
• Source: Universitaire Ziekenhuizen Leuven
• Status: Completed
• Start date: January 20, 2018
• Completion date: June 30, 2021